Evidence map›Paper›PMID 41866362›Full record

ArticleScientific reports2026

Persistence of vestibular function in the absence of glutamatergic transmission from hair cells.

Mohona Mukhopadhyay, Ruchi Modgekar, Aizhen Yang-Hood, Kevin K Ohlemiller, Valentin Militchin, Maolei Xiao, Zhijun Shen, Nicholas R Rensing, Michael Wong, Suh Jin Lee and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Autism associatedbioRxiv : the preprint server for biology · 2026
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors.

Mohona MukhopadhyayExperimental Otology Group, InnerEarLab, Department of Otolaryngology, Institute for Auditory Neuroscience, University Medical Center Göttingen, Göttingen, Germany.
Ruchi ModgekarExperimental Otology Group, InnerEarLab, Department of Otolaryngology, Institute for Auditory Neuroscience, University Medical Center Göttingen, Göttingen, Germany.
Aizhen Yang-HoodDepartment of Otolaryngology - Head and Neck Surgery, Washington University School of Medicine, St. Louis, MO, USA.
Kevin K OhlemillerDepartment of Otolaryngology - Head and Neck Surgery, Washington University School of Medicine, St. Louis, MO, USA.
Valentin MilitchinDepartment of Otolaryngology - Head and Neck Surgery, Washington University School of Medicine, St. Louis, MO, USA.
Maolei XiaoDepartment of Otolaryngology - Head and Neck Surgery, Washington University School of Medicine, St. Louis, MO, USA.
Zhijun ShenDepartment of Otolaryngology - Head and Neck Surgery, Washington University School of Medicine, St. Louis, MO, USA.
Nicholas R RensingDepartment of Neurology, Washington University School of Medicine, St. Louis, MO, USA.
Michael WongDepartment of Neurology, Washington University School of Medicine, St. Louis, MO, USA.
Suh Jin LeeDepartments of Neurobiology and Otolaryngology, Pittsburgh Center for Pain Research, University of Pittsburgh, Pittsburgh, PA, USA.
Rebecca P SealDepartments of Neurobiology and Otolaryngology, Pittsburgh Center for Pain Research, University of Pittsburgh, Pittsburgh, PA, USA.
Joseph C HoltDepartment of Otolaryngology, Department of Neuroscience, University of Rochester, Rochester, NY, USA.
Mark E WarcholDepartment of Otolaryngology - Head and Neck Surgery, Washington University School of Medicine, St. Louis, MO, USA.
Susan E MaloneyDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.
Carla M YuedeDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.
Mark A Rutherford *Department of Otolaryngology - Head and Neck Surgery, Washington University School of Medicine, St. Louis, MO, USA. rutherfordmark@wustl.edu.
Tina Pangrsic *Experimental Otology Group, InnerEarLab, Department of Otolaryngology, Institute for Auditory Neuroscience, University Medical Center Göttingen, Göttingen, Germany. tpangrs@gwdg.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Quantal synaptic transmission in vestibular endorgans is glutamatergic. Here, we investigated the vestibular phenotype of deaf Vglut3

Indexed as

Amino Acid Transport Systems, AcidicGlutamic AcidHair Cells, VestibularSynaptic TransmissionVestibule, LabyrinthAnimalsMiceMice, KnockoutVestibular NerveAmino Acid Transport Systems, AcidicGlutamic AcidSlc17a8 protein, mouseBalanceCalyxEPSCGlutamateNon-quantal and quantal synaptic transmission

Identifiers

PMID41866362
PMCPMC13153426

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.