Evidence map›Paper›PMID 41866301›Full record

Trial reportPsycho-oncology2026

A Randomized Controlled Trial: Evaluating the Sleep, Cancer and Rest (SleepCaRe) Trial to Improve Health-Related Quality of Life in Women Undergoing Chemotherapy for Breast Cancer.

Rebecca Wallace, Marliese Alexander, Daphne Day, Justine Diggens, Maria Ftanou, Veronica Aedo-Lopez, Bei Bei, Robert Blum, Frances Boyle, Trang Thuy Do and 8 more

Abstract readRandomized Controlled TrialMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Psycho-oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Rebecca WallaceSchool of Psychological Sciences, Monash University, Melbourne, Australia.ORCID https://orcid.org/0000-0001-8351-4231
Marliese AlexanderPharmacy Department, Peter MacCallum Cancer Centre, Melbourne, Australia.
Daphne DayDepartment of Oncology, Monash Health, Melbourne, Australia.
Justine DiggensPeople and Culture, Peter MacCallum Cancer Centre, Melbourne, Australia.
Maria FtanouDepartment of Psychology, Psychosocial Oncology Program, Peter MacCallum Cancer Centre, Melbourne, Australia.
Veronica Aedo-LopezDepartment of Oncology, Monash Health, Melbourne, Australia.
Bei BeiSchool of Psychological Sciences, Monash University, Melbourne, Australia.
Robert BlumDepartment of Oncology, Bendigo Cancer Centre, Bendigo Health, Bendigo, Australia.
Frances BoylePatricia Ritchie Centre for Cancer Care and Research Mater Hospital North Sydney, Australia and University of Sydney, Sydney, Australia.
Trang Thuy DoSchool of Psychological Sciences, Monash University, Melbourne, Australia.
Prudence A FrancisDepartment of Medical Oncology, Peter MacCallum Cancer Centre, Melbourne, Australia.
Sheila N GarlandDepartment of Psychology, Memorial University, St. John's, Newfoundland and Labrador, Canada.
Jordan MaccoraSchool of Psychological Sciences, Monash University, Melbourne, Australia.
Sharad SharmaDepartment of Medical Oncology, Ballarat Regional Integrated Cancer Centre, Grampians Health, Ballarat, Australia.
Lesley StaffordDepartment of Surgery, University of Melbourne, Melbourne, Australia.
Michelle WhiteDepartment of Oncology, Monash Health, Melbourne, Australia.
Duncan MortimerCentre for Health Economics, Monash University, Melbourne, Australia.ORCID https://orcid.org/0000-0002-7211-6454
Joshua F WileySchool of Psychological Sciences, Monash University, Melbourne, Australia.ORCID https://orcid.org/0000-0002-0271-6702

Funding

Friends of The Mater FoundationNational Health and Medical Research Council APP1178487
6 · The paper itself

Abstract

purposeAdvances in cancer treatment have led to improved survival rates, but challenges related to health-related quality of life (HRQoL) persist, often exacerbated by sleep disturbances. We present a pre-registered, secondary analysis of HRQoL from a trial of sleep interventions among women with early or advanced breast cancer receiving chemotherapy. PATIENTS AND

methodsThis 6-week, multisite, remotely-delivered, randomized controlled trial compared Cognitive Behavioral Therapy for Insomnia (CBT-I), Bright Light Therapy (BLT), their combination (CBT-I + BLT), and an active control (Sleep Hygiene Education, SHE) on HRQoL as measured by the PROMIS-Preference score (anchors: 0 "Dead" to 1 "Full health") at baseline, mid-point (3-weeks), post-intervention (6-weeks), and follow-ups (3&6-months). Interventions involved emails and tailored therapist-assisted intervention sessions.

results219 women receiving chemotherapy (M

conclusionCBT-I was associated with clinically meaningful improvements in HRQoL during chemotherapy. These findings support the integration of CBT-I into supportive care and highlight the need for tailored approaches for patients with advanced disease or persistent insomnia symptoms.

trial registrationACTRN12620001133921.

Indexed as

Antineoplastic AgentsBreast NeoplasmsCognitive Behavioral TherapyPhototherapyQuality of LifeSleep Initiation and Maintenance DisordersAdultAgedFemaleHumansMiddle AgedTreatment OutcomeAntineoplastic Agents

Identifiers

PMID41866301
PMCPMC13006194

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.