Trial reportAddictive behaviors2026
Shifting perceptions of e-cigarette risk: A secondary analysis from a nationwide, randomized controlled clinical trial of e-cigarettes among smokers.
Trial report in Addictive behaviors, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
introductionThe Food and Drug Administration (FDA) acknowledges there is a continuum of risk for tobacco products, and that e-cigarettes are generally less harmful than combustible cigarettes. However, most US adults perceive e-cigarettes as more harmful than cigarettes, and negative perceptions have increased over time. Media coverage surrounding e-cigarette or vaping product use-associated lung injury (EVALI) may have played a role in the changing relative harm perceptions about e-cigarettes and other tobacco products. The goal of the present study was to compare relative risk perceptions for cigarettes and e-cigarettes before, during, and after EVALI.
methodsThe present paper is a secondary data analysis from a US RCT conducted from May 2018 to March of 2022. Participants self-reported demographic information and perceptions of risk for both cigarettes and e-cigarettes at baseline. Changes in relative risk before, during, and after the EVALI outbreak, were compared using a piecewise constant model.
resultsRelative risk perceptions of e-cigarettes were significantly greater during (p < 0.001) and after EVALI (p < 0.001) compared to before the onset of EVALI. The differences in risk perceptions between cohorts of participants differed by race (p = 0.014), in that there was a significant increase in perceived risk of harm of e-cigarettes (relative risk perceptions) during and after EVALI compared to before EVALI for non-white participants (p < 0.001, p < 0.001).
conclusionsOnset of EVALI may have impacted relative risk perceptions of e-cigarettes compared to cigarettes. Non-white smokers were more likely to experience increased perceived risk of harm of e-cigarettes (relative risk perceptions). There is a need to continue monitoring risk perceptions among smokers, as negative relative risk perceptions may hinder switching from cigarettes to e-cigarettes.
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