Evidence map›Paper›PMID 41865333›Full record

ArticleWorld journal of urology2026

Experience of 5 years adjustable continence therapy (ProACT): the surgical learning curve and patient outcomes.

Lisa M de Zeeuw, Coen H H Christiaans, Sebastiaan Remmers, Bertil F M Blok, Alexander B Stillebroer

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Article in World journal of urology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lisa M de ZeeuwDepartment of Urology, Erasmus University Medical Center, Rotterdam, The Netherlands. l.dezeeuw@erasmusmc.nl.ORCID https://orcid.org/0009-0006-3483-8006
Coen H H ChristiaansDepartment of Urology, Erasmus University Medical Center, Rotterdam, The Netherlands.ORCID https://orcid.org/0009-0006-7324-1608
Sebastiaan RemmersDepartment of Urology, Erasmus University Medical Center, Rotterdam, The Netherlands.ORCID https://orcid.org/0000-0001-9530-6448
Bertil F M BlokDepartment of Urology, Erasmus University Medical Center, Rotterdam, The Netherlands.ORCID http://orcid.org/0000-0001-9354-7395
Alexander B StillebroerDepartment of Urology, Erasmus University Medical Center, Rotterdam, The Netherlands.ORCID https://orcid.org/0009-0004-3622-1582

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePost-prostatectomy urinary incontinence (PPI) significantly impacts quality of life. While an artificial urinary sphincter is the standard surgical treatment for PPI, adjustable continence therapy balloons (ProACT) have emerged as a less invasive alternative over the past two decades. ProACT implantation is considered technically challenging and limited to three high-volume Dutch medical centers, yet little is known about the surgical learning curve. This study aims to assess the learning curve to inform training requirements for ProACT implantation.

methodsThis retrospective single-center study included all ProACT implantations performed by one urologist at Erasmus University medical Center, Rotterdam. Surgery success was defined as postoperative use of a maximum of one 'safety pad', less than 10 mL urine loss or ≥ 95% subjective improvement of continence. Multivariable logistic regression assessed the learning curve.

resultsA total of 108 surgeries between 2019 and 2024 were included, of which 15 were supervised by an experienced surgeon. No statistical relation was found between the progressive surgeon's experience and surgical success (per 10 surgeries, OR 0.89, 95%CI: 0.75-1.07, p = 0.2). Preoperative incontinence (pads/day) was statistically significantly associated with surgical success (OR 0.65, 95%CI: 0.47-0.89, p = 0.009). The overall surgical success rate was 61%, with an additional 20% achieving > 50% continence improvement. Complication rate within six months was 21% of which six (5.6%) included explantations of the ProACT device.

conclusionProACT implantation achieves consistent outcomes after brief supervised training, with no statistically significant learning curve. This supports a broader adoption of this technique by urologists treating PPI.

Indexed as

Learning CurvePostoperative ComplicationsProstatectomyProsthesis ImplantationUrinary IncontinenceAgedHumansMaleMiddle AgedRetrospective StudiesTime FactorsTreatment OutcomePostprostatectomySuccess rateUrinary incontinenceVoiding-frequency diary

Identifiers

PMID41865333
PMCPMC13006453

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.