Evidence map›Paper›PMID 41865160›Full record

ArticleScientific reports2026

Optimising the caffeine nap for counteracting driver sleepiness in CPAP treated obstructive sleep apnoea patients.

Ashleigh J Filtness, Karl A Miller, Sally Maynard, Adam Asmal, Thomas Kerwin, Andrew Hall, Anna Anund

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ashleigh J FiltnessTransport Safety Research Centre, Loughborough University, Loughborough, UK. a.j.filtness@lboro.ac.uk.
Karl A MillerTransport Safety Research Centre, Loughborough University, Loughborough, UK.
Sally MaynardTransport Safety Research Centre, Loughborough University, Loughborough, UK.
Adam AsmalTransport Safety Research Centre, Loughborough University, Loughborough, UK.
Thomas KerwinThe Ohio State University, Columbus, USA.
Andrew HallThe Hanning Sleep Laboratory, University Hospitals of Leicester NHS Trust, Leicester, UK.
Anna AnundSwedish National Road and Transport Research Institute (VTI), Linköping, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Driver sleepiness contributes to a substantial proportion of road crashes. Drivers experiencing sleepiness are advised to take a break and have a caffeinated drink followed by a short nap (caffeine nap). However, previous research advocating this countermeasure has not considered participants with obstructive sleep apnoea (OSA), the most prevalent sleep disorder. Across three studies the effectiveness of caffeine, nap opportunity and caffeine nap countermeasures on subjective sleepiness (KSS), objective sleepiness (Alpha and Theta activity) and driving performance (standard deviation of lateral position and out-of-lane events) are considered. Twenty-one CPAP treated OSA participants (mean age = 59 years) engaged with a protocol of six laboratory visits: one after a normal night's CPAP-treated sleep and five after sleep restriction (4 h CPAP-treated sleep), driving a monotonous simulated scenario before and after a countermeasure. Results showed that two cans of coffee (255 mg caffeine) mitigated driver sleepiness more than one can (127.5 mg) and little benefit to 30 min compared with 15 min nap opportunity. An optimised caffeine nap of two coffees followed by a 15 min nap opportunity provides some temporary benefit, but for OSA drivers a caffeine nap offers little practical improvement compared to two coffees alone. All countermeasures are temporary and cannot replace a good night of sleep before driving.

Indexed as

Automobile DrivingCaffeineContinuous Positive Airway PressureSleepSleep Apnea, ObstructiveSleepinessAgedCoffeeFemaleHumansMaleMiddle AgedCaffeineCoffeeCaffeine napCountermeasureDriver drowsinessDriver fatigueNappuccinoOSA

Identifiers

PMID41865160
PMCPMC13144385

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.