Evidence map›Paper›PMID 41865089›Full record

ArticlePlant foods for human nutrition (Dordrecht, Netherlands)2026

Functional Potential of Peruvian Fava Bean Flours in Bread: Antioxidant Activity and Phenolic Bioaccessibility.

Alessandra Andréa Pereira Nicolau, Rebeca Salvador-Reyes, Maria Teresa Pedrosa Silva Clerici, Bruno Martins Dala-Paula

Abstract read
In one paragraph

Article in Plant foods for human nutrition (Dordrecht, Netherlands), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Rethinking Plant Proteins: Innovations in Nutrition, Processing, and Food Development.Plant foods for human nutrition (Dordrecht, Netherlands) · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Alessandra Andréa Pereira NicolauFaculdade de Nutrição, Universidade Federal de Alfenas (UNIFAL-MG), Alfenas, MG, Brazil.ORCID http://orcid.org/0000-0003-0883-6622
Rebeca Salvador-ReyesDepartamento de Ciência de Alimentos e Nutrição, Faculdade de Engenharia de Alimentos, Universidade Estadual de Campinas, Campinas, SP, Brazil.ORCID http://orcid.org/0000-0002-7422-5742
Maria Teresa Pedrosa Silva ClericiDepartamento de Ciência de Alimentos e Nutrição, Faculdade de Engenharia de Alimentos, Universidade Estadual de Campinas, Campinas, SP, Brazil.ORCID http://orcid.org/0000-0002-8445-336X
Bruno Martins Dala-PaulaFaculdade de Nutrição, Universidade Federal de Alfenas (UNIFAL-MG), Alfenas, MG, Brazil. brunodala@gmail.com.ORCID http://orcid.org/0000-0002-5022-4796

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plant-based foods are increasingly valued for their health-promoting and sustainable attributes. Among legumes, fava bean (Vicia faba L.) is notable for its nutritional density and bioactive compounds. This study evaluated the effect of partially substituting wheat flour with raw flours from three Peruvian cultivars (Verde, Quelcao, and Peruanita) on antioxidant potential and phenolic bioaccessibility in bread. Six bread formulations were prepared by replacing 10 and 20% of wheat flour with fava bean flours, alongside a control (100% wheat flour). Antioxidant activity was assessed using ABTS•⁺ and DPPH assays, while total phenolic content (TPC) and total flavonoid content (TFC) were measured spectrophotometrically. Phenolic bioaccessibility and antioxidant activity were further examined through in vitro gastrointestinal digestion following the INFOGEST protocol. Compared with the control, fava bean flours showed significantly higher antioxidant potential (ABTS 26.13 µmol TE/g; DPPH 0.90 µmol TE/g), TPC (1.61 mg GAE/g), and TFC (0.80 mg CE/g), with Peruanita achieving the highest values. Partial substitution enhanced the antioxidant properties of breads, particularly at 20%. After digestion, both breads and flours exhibited greater antioxidant potential and phenolic bioaccessibility, suggesting the release of bound compounds. Partial substitution of wheat flour with Peruvian fava bean flours improves bread’s nutritional and functional properties by enhancing antioxidant potential and phenolic bioaccessibility. These results underscore the value of underutilized Andean legumes as sustainable ingredients for developing functional bakery products with added health benefits.

Indexed as

AntioxidantsBreadFlourPhenolsVicia fabaBiological AvailabilityDigestionFlavonoidsHumansNutritive ValuePeruTriticumAntioxidantsFlavonoidsPhenolsAntioxidantsBakingPulseSustainabilityVicia fava L.

Identifiers

PMID41865089
PMCPMC13005775

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.