ArticleScientific reports2026
Comparative metabolomic and physiological analysis uncovers distinct drought tolerance mechanisms in four rice cultivars.
Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Drought Stress Mediated Changes in Food Crops: Mechanisms and Remediation Strategies.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Drought stress is a major abiotic challenge threatening global food security by negatively affecting rice morphology, physiology, and biochemistry. This study explored the morpho-physiological and metabolomic responses of four rice cultivars (Giza 179, Hassawi, Super 300, and Y EGY) to drought stress induced by 15% PEG for 14 days. Measurements included fresh weight, relative water content (RWC), proline content, and plant height, while leaf and root tissues underwent detailed GC-MS metabolomic profiling followed by multivariate analyses such as PCA, VIP scoring, volcano plots, and pathway enrichment. Results showed Y EGY experienced the greatest decline in fresh weight, whereas Giza 179 maintained higher biomass. Stress tolerance indices ranked the cultivars as Giza 179 (85.2%), Super 300 (65.5%), Hassawi (61.7%), and Y EGY (52.2%). Metabolomic analysis identified 114 leaf and 97 root metabolites, with 40 showing VIP > 1.0. Volcano plot analysis revealed distinct variety-specific responses: Giza 179 demonstrated broad metabolic activation with upregulation of methylgalactoside, glycerol-3-phosphate, and citric acid in leaves; Hassawi showed effective targeted responses with strategic trehalose upregulation, while Y EGY exhibited extensive root metabolic disruption. Pathway enrichment identified alanine, aspartate, and glutamate metabolism, arginine and proline metabolism, and the TCA cycle as most significantly affected in leaves, while the TCA cycle was the main response pathway in roots. Post-hoc analysis confirmed that drought-tolerant cultivars exhibited more balanced metabolic regulation. These findings suggest that superior drought tolerance is associated with either efficient targeted metabolic responses that conserve resources (Hassawi, Super 300) or robust integrated mechanisms that coordinate osmoregulation and metabolic reprogramming (Giza 179), providing valuable insights for breeding drought-tolerant rice varieties.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.