Evidence map›Paper›PMID 41864971›Full record

ArticleScientific reports2026

A multi-scale adaptive filtering and AtRes_SRU-transformer synergy for breast cancer histopathology classification.

N M Saravana Kumar, Manoj Kumar Kandala, Parag Ravikant Kaveri, Nithya Rekha Sivakumar

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Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

N M Saravana KumarDean cum Professor, School of Computing, Nehru Institute of Engineering and Technology, Coimbatore, 641 105, India. saravanakumaar2008@gmail.com.
Manoj Kumar KandalaResearch Scholar, Faculty of Computer Science and Information Engineering, Anna University, Chennai, 600 025, India.
Parag Ravikant KaveriSymbiosis Institute of Computer Studies and Research, Symbiosis International (Deemed University), Pune, India.
Nithya Rekha SivakumarDepartment of Computer Sciences, College of Computer and Information Sciences, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh, 11671, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Biomedical image analysis is also crucial in the contemporary healthcare system as it facilitates correct diagnosis of diseases, treatment planning, and clinical decision-making. As novel imaging methods like MRI, histopathology and chest X-ray have appeared, the necessity of automated systems that could effectively work with extensive image data of different complexity has grown. The main difficulty, however, is to strike the right balance between the complexity of biomedical images and computational efficiency because, most of the time, these images are large-scale, high-resolution, and have a large tissue variation, noise, and inter and intra-class differences. Conventional deep learning models such as CNNs and RNNs cannot handle such issues and at the same time achieve high diagnostic accuracy and computational efficiency particularly in real-time clinical scenarios. The current paper introduces the pseudo-name ImTranNet-TriCore, which is a new model of deep learning developed to facilitate the categorization of biomedical images. The suggested model combines three important innovations including a Learnable Multi-Scale Adaptive Filtering module (LM-AdaFilter), a Dual-Path Attentive Residual SRU (DP-AtRes-SRU) and a Multi-Head Hybrid Transformer (MHHT). The components all contribute to the challenging issues of noise-reduction, spatial-temporal features learning, and global-contextual reasoning in the biomedical images. LM-AdaFilter is a dynamically-adjusted filtering parameter to retain diagnostically important features, whereas DP-AtRes-SRU can capture the spatial as well as the temporal relationships. The MHHT reconciles the local features and global context to increase feature fusion and boost classification accuracy. The main goal of the paper is to suggest the computationally effective and interpretable biomedical image classification model. The ImTranNet-TriCore model was put to test on conventional biomedical datasets and it performed at 95.92 accuracy. Precision (97.83% in Brain MRI, 97.67% in Chest X-ray), Recall (93.75% in Brain MRI, 87.50% in Chest X-ray) and F1-Score indicated the strong performance of the model in distinguishing between positive and negative cases, as well as reducing the number of false positives. The findings emphasize the fact that ImTranNet-TriCore is superior to the conventional models such as CNNs, RNNs, and standalone transformers, in working on complex and noisy biomedical data, and is therefore applicable in the real-life clinical context.

Indexed as

Breast NeoplasmsDeep LearningImage Interpretation, Computer-AssistedImage Processing, Computer-AssistedAlgorithmsFemaleHumansMagnetic Resonance ImagingBiomedical ImagingDeep LearningHybrid TransformerMedical Image AnalysisMulti-Scale FilteringSpatial-Temporal Modeling

Identifiers

PMID41864971
PMCPMC13144486

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.