Evidence map›Paper›PMID 41864948›Full record

ArticleBMC medical informatics and decision making2026

Machine learning algorithms for identifying tuberculous pericardial effusion: insights from a retrospective study in Vietnam.

Hai Phuong Nguyen Tran, Kha Minh Nguyen, Nam Nhat Nguyen, Vi Tuong Dang, Sang Quang Ly, Tai Nhat Nguyen, Lan Thanh Phan, Sy Van Hoang

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Article in BMC medical informatics and decision making, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Hai Phuong Nguyen TranDepartment of Interventional Cardiology, Cho Ray Hospital, Ho Chi Minh City, 700000, Vietnam.
Kha Minh NguyenDepartment of Internal Medicine, Faculty of Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, 700000, Vietnam.
Nam Nhat NguyenHanh Phuc International Hospital, Ho Chi Minh City, 700000, Vietnam.
Vi Tuong DangDepartment of Internal Medicine, Faculty of Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, 700000, Vietnam.
Sang Quang LyDepartment of Interventional Cardiology, Cho Ray Hospital, Ho Chi Minh City, 700000, Vietnam.
Tai Nhat NguyenDepartment of Interventional Cardiology, Cho Ray Hospital, Ho Chi Minh City, 700000, Vietnam.
Lan Thanh PhanDepartment of Cardiology, Cho Ray Hospital, Ho Chi Minh City, 700000, Vietnam.
Sy Van HoangDepartment of Internal Medicine, Faculty of Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, 700000, Vietnam. hoangvansy@ump.edu.vn.ORCID 0000-0002-3984-648X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTuberculous pericardial effusion (TPE) presents significant diagnostic challenges due to its nonspecific clinical presentation and similarities with other types of pericardial effusion. The available data on the use of artificial intelligence for predicting TPE is minimal and needs further expansion. This study aimed to evaluate the diagnostic performance of various machine learning algorithms (MLAs) in identifying TPE among patients with pericardial effusion. MATERIALS AND

methodsA retrospective study was conducted at Cho Ray Hospital in Vietnam from 2010 to 2020. Eight MLAs-logistic regression, K-nearest neighbor, support vector machine, random forest, Lagrangian support vector machine, random tree (RT), chi-square automatic interaction detection, and C5.0-were evaluated for their diagnostic accuracy. The performance metrics included sensitivity, specificity, positive predictive value, negative predictive value, positive likelihood ratio, negative likelihood ratio, and accuracy.

resultsOf the 248 patients with pericardial effusion, 52 were confirmed to have tuberculosis. Predictive factors for TPE included male sex, a lower body mass index, and fever at admission. The RT model demonstrated the highest accuracy (94%) and area under the curve (AUC) (0.971). Pericardial fluid adenosine deaminase was identified as the most significant feature for TPE diagnosis, with an optimal threshold of 27.8 U/L, a sensitivity of 80.8% and a specificity of 84.2%.

conclusionMachine learning algorithms, particularly the random tree model, demonstrate promising potential for improving TPE diagnosis through noninvasive data analysis. However, successful implementation requires external validation and careful consideration of local healthcare capabilities.

Indexed as

Machine LearningPericardial EffusionPericarditis, TuberculousTuberculosisAdultAlgorithmsClassification AlgorithmsFemaleHumansMaleMiddle AgedPrediction AlgorithmsPredictive Learning ModelsRandom ForestRetrospective StudiesVietnamMachine learningPericardial effusionPredictionRandom treeTuberculosis

Identifiers

PMID41864948
PMCPMC13130456

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