Evidence map›Paper›PMID 41863712›Full record

Observational studyJapanese journal of ophthalmology2026

Collaborative care for retinal artery occlusion by ophthalmologists and vascular neurologists: management of systemic complications.

Ayane Kamikawa, Kohei Kiyohara, Mariko Shirane, Sakurako Shimokawa, Takahiro Hisai, Yoshiyuki Kobayashi, Muneo Yamaguchi, Shoji Notomi, Keijiro Ishikawa, Takuya Kiyohara and 6 more

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Japanese journal of ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Ayane KamikawaDepartment of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, 812-8582, Japan.
Kohei KiyoharaDepartment of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, 812-8582, Japan.
Mariko ShiraneDepartment of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, 812-8582, Japan.
Sakurako ShimokawaDepartment of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, 812-8582, Japan.
Takahiro HisaiDepartment of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, 812-8582, Japan.
Yoshiyuki KobayashiDepartment of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, 812-8582, Japan.
Muneo YamaguchiDepartment of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, 812-8582, Japan.
Shoji NotomiDepartment of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, 812-8582, Japan.
Keijiro IshikawaDepartment of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, 812-8582, Japan.
Takuya KiyoharaDepartment of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Yoshinobu WakisakaDepartment of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Tetsuro AgoDepartment of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Takanari KitazonoDepartment of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Koh-Hei SonodaDepartment of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, 812-8582, Japan.
Kuniyuki NakamuraDepartment of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Yusuke MurakamiDepartment of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, 812-8582, Japan. murakami.yusuke.407@m.kyushu-u.ac.jp.ORCID http://orcid.org/0000-0002-3761-1732

Funding

Japanese Ministry of Education, Culture, Sports, Science, and Technology #22H03242Japanese Ministry of Education, Culture, Sports, Science, and Technology #22KK0136
6 · The paper itself

Abstract

purposeRetinal artery occlusion (RAO) is frequently associated with cerebrovascular and cardiovascular events, and guidelines highlight the need for secondary prevention. Since 2019, our hospital has implemented collaborative care between ophthalmologists and vascular neurologists for acute RAO, and here, we report the clinical outcomes before and after this approach. STUDY

designRetrospective observational study.

methodsEighty-seven patients (mean age: 72.2 ± 13.4 years; 40 male) diagnosed with central retinal artery occlusion (CRAO), branch retinal artery occlusion (BRAO), or cilioretinal artery occlusion (CLRAO) at Kyushu University Hospital between March 2013 and May 2024 were retrospectively analyzed, and information on patient backgrounds, ocular and systemic examinations, and treatments was obtained.

resultsThe disease types were CRAO in 58, BRAO in 24, and CLRAO in 5 patients. Systemic complications before and after collaborative care included hypertension (67% before vs 79% after), diabetes (28% vs 17%), dyslipidemia (41% vs 44%), cerebrovascular diseases (21% vs 10%), carotid artery diseases (18% vs 40%, P = 0.03), and cardiac diseases (3% vs 27%, P = 0.002). After initiation of collaborative care, the causes of RAO were identified as large-artery atherosclerosis (LAA) in 29%, cardioembolism (CE) in 23%, undetermined in 38%, other determined in 8%, and insufficient evaluation in 2% of the patients. Anticoagulants were commonly prescribed for patients with CE, whilst antiplatelet agents were prescribed for those with LAA or embolic stroke of undetermined source (ESUS).

conclusionIntegrated collaborative care facilitates prompt detection of systemic vascular complications and initiation of secondary preventive treatments in patients with RAO.

Indexed as

Disease ManagementNeurologistsOphthalmologistsRetinal Artery OcclusionAgedAged, 80 and overFemaleHumansMaleMiddle AgedRetrospective StudiesCollaborative careRetinal artery occlusionSystemic complicationTreatment

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.