SynthesisObesity surgery2026
Gastroesophageal Reflux Disease Outcomes after Sleeve Gastrectomy with One Anastomosis Transit Bipartition: A Systematic Review and Meta-analysis.
Synthesis in Obesity surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSleeve gastrectomy (SG) is the most commonly performed bariatric procedure worldwide, but gastroesophageal reflux disease (GERD) remains a significant long-term complication affecting 20–35% of patients. Transit bipartition (TB) procedures have emerged as potential solutions for managing GERD while maintaining metabolic benefits. This systematic review evaluates GERD outcomes following TB procedures.
methodsA systematic search of PubMed, Embase, Cochrane CENTRAL, and Web of Science was conducted through January 5, 2025, following PRISMA 2020 guidelines. Quality assessment used the MINORS instrument. Random-effects meta-analysis using Freeman-Tukey double arcsine transformation was performed in R (packages: meta 6.5-0, metafor 4.4-0). Heterogeneity was assessed using I², τ², and Cochran’s Q. Publication bias was evaluated using funnel plots and Egger’s test.
resultsSeven studies comprising 2,912 patients met inclusion criteria. The pooled GERD resolution rate was 88.4% (95% CI: 78.6–94.5%; I²=64.8%). De novo GERD occurred in 4.9% (95% CI: 2.8–7.8%). Leave-one-out sensitivity analysis demonstrated stable estimates (range: 85.7–89.2%). Publication bias assessment (Egger’s p = 0.089) with trim-and-fill adjustment suggested potential overestimation by approximately 4% points (adjusted estimate: 84.1%).
conclusionsTransit bipartition procedures demonstrate favorable short-term GERD outcomes with resolution exceeding 85% and low de novo GERD incidence below 5%. However, the evidence is limited by study design, heterogeneity, and short follow-up. These procedures offer effective weight loss with favorable GERD outcomes compared to standard sleeve gastrectomy.
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