ArticleEmerging infectious diseases2026
Environmental and Phylogenetic Investigations of Aspergillus flavus Outbreak Linked to Contaminated Building Materials, Denmark, 2025.
Article in Emerging infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Distinct Phenotype and Secondary Metabolite Profile Mark a DominantJournal of fungi (Basel, Switzerland) · 2026Article
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Authors and funding
10 authors.
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Abstract
An Aspergillus flavus outbreak occurred in a tertiary hospital in Denmark. We compared environmental sampling methods, investigated the outbreak through short tandem-repeat genotyping, STRAfla, and analyzed isolate phylogeny using whole-genome sequencing. Paired sampling revealed that air sampling underestimated A. flavus burden (8 CFU/81 air samples vs. 585 CFU/81 surface samples), and culturing at 37°C was superior to 25°C (risk ratio 1.77; p<0.001). STRAfla (n = 145) confirmed clonality of the outbreak isolates. Active growth was identified in a kitchen inside the affected ward. Genetically related isolates were also found in the Department of Clinical Microbiology and in 4 unrelated wood-based building materials from retailers in Denmark. Phylogenetic analyses of 167 isolates supported introduction of A. flavus from building materials. We hypothesize that water damage enabled germination of dormant spores in precontaminated wood-based products. Our findings highlight a risk factor for outbreaks and should inform future hospital construction and infection prevention strategies.
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