Evidence map›Paper›PMID 41863438›Full record

ArticleAnalytical chemistry2026

Lessons Learned in Orbitrap MS-Based Isotope Ratio Analysis of Organic Acid Mixtures.

Hugo G Machado, Elliott P Mueller, Júlio C O Ribeiro, Giovanni B Bevilaqua, Gabriel F Dos Santos, Alexandre A Ferreira, Ygor S Rocha, Surjyendu Bhattacharjee, John M Eiler, Boniek Gontijo

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Analytical chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hugo G MachadoChemistry Institute, Federal University of Goiás, Goiánia, Goiás 74690-900, Brazil.ORCID 0000-0002-9222-6917
Elliott P MuellerDivision of Geological and Planetary Sciences, California Institute of Technology, Pasadena, California 91125, United States.
Júlio C O RibeiroChemistry Institute, Federal University of Goiás, Goiánia, Goiás 74690-900, Brazil.
Giovanni B BevilaquaChemistry Institute, Federal University of Goiás, Goiánia, Goiás 74690-900, Brazil.ORCID 0000-0002-9210-870X
Gabriel F Dos SantosChemistry Institute, Federal University of Goiás, Goiánia, Goiás 74690-900, Brazil.ORCID 0000-0002-4155-6238
Alexandre A FerreiraDivision of Geochemistry, PETROBRAS Research and Development Center (CENPES), PETROBRAS, Rua Horácio Macedo, Ilha do Fundão, Rio de Janeiro, RJ 21941-915, Brazil.ORCID 0000-0001-6257-960X
Ygor S RochaDivision of Geochemistry, PETROBRAS Research and Development Center (CENPES), PETROBRAS, Rua Horácio Macedo, Ilha do Fundão, Rio de Janeiro, RJ 21941-915, Brazil.
Surjyendu BhattacharjeeDivision of Geological and Planetary Sciences, California Institute of Technology, Pasadena, California 91125, United States.
John M EilerDivision of Geological and Planetary Sciences, California Institute of Technology, Pasadena, California 91125, United States.
Boniek GontijoChemistry Institute, Federal University of Goiás, Goiánia, Goiás 74690-900, Brazil.ORCID 0000-0003-1197-4284

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stable isotope analysis is a vital tool across chemistry, geology, and environmental science, but conventional Isotope Ratio Mass Spectrometry (IRMS) techniques have limited capabilities for site-specific or multiply substituted ("clumped") isotope analyses, and are particularly limited for analyses of complex mixtures without prior analyte purification. This study addresses this gap by employing a high-resolution Orbitrap mass spectrometer to directly measure the

Identifiers

PMID41863438
PMCPMC13063220

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.