Evidence map›Paper›PMID 41863312›Full record

Trial reportInterdisciplinary cardiovascular and thoracic surgery2026

Early Supervised Incremental Resistance Training Versus Standard Care Following Median Sternotomy-A Preliminary Analysis of a Randomized Controlled Trial.

Nur Ayub Mohd Ali, Mohd Ali Katijjahbe, Doa El-Ansary, Nor Azura Azmi, Tze Huat Chong, Alistair Royse, Ahmad Lutfi Ahmad Bazli, Hairulfaizi Haron, Yuen Wen Adzim Poh, Mohd Rizal Abdul Manaf and 1 more

Abstract readRandomized Controlled TrialClinical Trial, Phase IIComparative Study
In one paragraph

Trial report in Interdisciplinary cardiovascular and thoracic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Nur Ayub Mohd AliCardiovascular Research and Pulmonary Group, Universiti Kebangsaan Malaysia (UKM), 43600 Bangi, Malaysia.ORCID 0000-0002-0142-6658
Mohd Ali KatijjahbeCardiovascular Research and Pulmonary Group, Universiti Kebangsaan Malaysia (UKM), 43600 Bangi, Malaysia.ORCID 0000-0002-1348-3617
Doa El-AnsarySchool of Health and Biomedical Sciences, RMIT University, 3083 Bundoor, Australia.
Nor Azura AzmiPhysiotherapy Programme, Center for Rehabilitation and Special Needs Studies, Faculty of Health Sciences, UKM, 50300 Kuala Lumpur, Malaysia.ORCID 0000-0003-3191-756X
Tze Huat ChongDepartment of Surgery, Hospital Taiping, 34000 Taiping, Perak, Malaysia.
Alistair RoyseDepartment of Surgery, Faculty of Medicine UKM, 56000 Cheras, Malaysia.ORCID 0000-0002-4449-663X
Ahmad Lutfi Ahmad BazliSherwood Forest Hospitals NHS Foundation Trust, NG6 8BB Nottingham, United Kingdom.ORCID 0009-0000-0614-0285
Hairulfaizi HaronHeart and Lung, Centre Hospital Canselor Tuanku Mukhriz, UKM, 56000 Cheras, Malaysia.
Yuen Wen Adzim PohDepartment of Surgery, Faculty of Medicine UKM, 56000 Cheras, Malaysia.
Mohd Rizal Abdul ManafDepartment of Public Health Medicine, Faculty of Medicine UKM, Malaysia.ORCID 0000-0002-0814-8376
Muhammad Ishamuddin IsmailCardiovascular Research and Pulmonary Group, Universiti Kebangsaan Malaysia (UKM), 43600 Bangi, Malaysia.ORCID 0009-0006-7171-6331

Funding

UKM Research University
6 · The paper itself

Abstract

objectivesTo evaluate the safety and feasibility of implementing a supervised incremental UL resistance training program in the early postoperative period, and to investigate its initial effects on UL function and patient-reported pain at four weeks and three months after median sternotomy.

methodsThis study is a report of the preliminary analysis of a phase II prospective, double-blind, randomized controlled trial that tested the Early Supervised Incremental Resistance Training intervention following a median sternotomy and explored its effects on upper limb function and patient-reported pain at 4 weeks and at 3 months.Primary outcomes were safety (defined by sternal wound complications); feasibility (assessed by recruitment and adherence); and upper limb function (measured by the Unsupported Upper Limb Exercise Test). Secondary outcomes included the Functional Difficulty Questionnaire Shortened Version and pain using the Numeric Rating Scale. Assessments occurred at baseline, discharge, 4 weeks and 3 months postoperatively.

resultsFifty-five participants were recruited (Early Supervised Incremental Resistance Training, n = 27; standard care, n = 28). No sternal complications occurred (relative risk, 0.963; 95% confidence interval, 0.057-16.21). Adherence was 80%, with no dropouts. Between-group differences in the Unsupported Upper Limb Exercise Test were not significant at 4 weeks (mean difference (MD), 1.49; 95% confidence interval, -4.62 to 7.16) or 3 months (mean difference (MD) 1.19; 95% confidence interval, -5.58 to 7.79). No significant differences were found for the Functional Difficulty Questionnaire Shortened Version or the Numeric Rating Scale. Within-group analyses showed significant improvements in the Unsupported Upper Limb Exercise Test, the Functional Difficulty Questionnaire Shortened Version and the Numeric Rating Scale over time.

conclusionsThe Early Supervised Incremental Resistance Training was safe, feasible and well-accepted in the acute inpatient setting, with strong recruitment and adherence and no adverse events.

trial registrationISRCTN 17842822, registered 11 March 2020.

Indexed as

Resistance TrainingSternotomyUpper ExtremityAgedDouble-Blind MethodFeasibility StudiesFemaleHumansMaleMiddle AgedPain MeasurementPostoperative PainProspective StudiesRecovery of FunctionTime FactorsTreatment Outcomeincremental resistance training exercisemedian sternotomyrandomized controlled trialupper limbs

Identifiers

PMID41863312
PMCPMC13143420

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.