Evidence map›Paper›PMID 41863130›Full record

ReviewCurrent medical imaging2026

Advancements in Endoscopic Optical Coherence Tomography for Urothelial Carcinoma: Research Progress and Clinical Applications

Yongkun Zhu, Qiang Hu, Rui Zhang, Guangyuan Zhang, Ming Chen

Abstract readReview
In one paragraph

Review in Current medical imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yongkun ZhuDepartment of Urology, Affiliated Zhongda Hospital of Southeast University, Nanjing, 210009, China.
Qiang HuDepartment of Urology, Affiliated Zhongda Hospital of Southeast University, Nanjing, 210009, China.
Rui ZhangDepartment of Ophthalmology, Affiliated Zhongda Hospital of Southeast University, Nanjing, 210009, China.
Guangyuan ZhangDepartment of Urology, Affiliated Zhongda Hospital of Southeast University, Nanjing, 210009, China.
Ming ChenDepartment of Urology, Affiliated Zhongda Hospital of Southeast University, Nanjing, 210009, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis review summarizes recent advances in endoscopic optical coherence tomography for urothelial carcinoma, focusing on technical features, clinical applications, and future directions. MATERIALS AND

methodsThis is a narrative review based on a literature review of databases such as PubMed, Embase, Web of Science, and the Cochrane Library, from January 2000 to March 2025. OCT imaging diagnosed with urothelial carcinoma. Studies meeting the following inclusion criteria are eligible, including reports describing the technical aspects or clinical applications (such as diagnosis, staging, intraoperative guidance, or postoperative monitoring) of OCT imaging in the care of patients with urothelial carcinoma. The results of the study have been categorised.

resultsOCT demonstrated high-resolution imaging and real-time capabilities, enabling differentiation of malignant from normal urothelial tissues. Clinical studies confirmed its value in tumor staging and intraoperative guidance, with strong concordance to histopathology. OCT improved diagnostic sensitivity and specificity when combined with conventional cystoscopy and showed potential in monitoring treatment response and detecting recurrence. DISCUSSION: OCT offers a non-invasive, precise imaging modality with significant advantages over traditional diagnostic methods. However, limitations remain, including restricted imaging depth and variability across clinical protocols. Standardization and broader clinical validation are needed to ensure consistent adoption.

conclusionEndoscopic OCT represents a transformative tool for UC management. With further technological innovations and standardized protocols, it is expected to enhance early detection, intraoperative guidance, and long-term patient outcomes.

Indexed as

Carcinoma, Transitional CellTomography, Optical CoherenceUrinary Bladder NeoplasmsCystoscopyHumansNeoplasm StagingSensitivity and SpecificityCancer stagingIntraoperative guidance.Optical coherence tomographyTreatment monitoringUrothelial carcinoma

Identifiers

PMID41863130
PMCPMC13639909

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.