Evidence map›Paper›PMID 41863124›Full record

Observational studyCurrent HIV research2026

Hepatitis B Vaccination Rates and Risk Factors Affecting Vaccine Response in People Living with HIV in Turkey.

Arzu Mirza, Mehmet Cabalak, Ozgur Gunal, Aslıhan Candevir, Bircan Kayaaslan, İlkay Karaoglan, Hatun Öztürk Cerik, Deniz Ozer, İlknur Erdem, Tuba Damar Çakırca and 12 more

Abstract readMulticenter StudyObservational Study
PubMed Publisher
In one paragraph

Observational study in Current HIV research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Arzu MirzaAnkara Provincial Health Directorate Public Health Services Presidency, Ankara, Turkiye.ORCID 0000-0001-8713-3671
Mehmet CabalakDepartment of Infectious Diseases and Clinical Microbiology, Hatay Mustafa Kemal University Hospital, Hatay, Turkiye.ORCID 0000-0003-1148-2247
Ozgur GunalDepartment of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Samsun University, Samsun Training and Research Hospital, Samsun, Turkiye.
Aslıhan CandevirDepartment of Infectious Diseases and Clinical Microbiology, Cukurova University Medical Faculty Hospital, Adana, Turkiye.ORCID 0000-0001-9340-516X
Bircan KayaaslanDepartment of Infectious Diseases and Clinical Microbiology, Ankara Bilkent City Hospital, Ankara, Turkiye.ORCID 0000-0001-5225-8319
İlkay KaraoglanDepartment of Infectious Diseases and Clinical Microbiology, Gaziantep University Medical Faculty Hospital, Gaziantep, Turkiye.ORCID 0000-0002-6767-4523
Hatun Öztürk CerikDepartment of Infectious Diseases and Clinical Microbiology, Ordu University Training and Research Hospital, Ordu, Turkiye.ORCID 0000-0003-0277-5443
Deniz OzerDepartment of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Manisa Celal Bayar University, Hafsa Sultan Hospital, Manisa, Turkiye.
İlknur ErdemDepartment of Infectious Diseases and Clinical Microbiology, Tekirdağ Namık Kemal University, Faculty of Medicine Hospital, Tekirdağ, Turkiye.ORCID 0000-0003-2262-6525
Tuba Damar ÇakırcaDepartment of Infectious Diseases and Clinical Microbiology, Şanlıurfa Training and Research Hospital, Şanlıurfa, Turkiye.ORCID 0000-0002-1706-230X
Dilek BulutDepartment of Infectious Diseases and Clinical Microbiology, Ankara Etlik City Hospital, Ankara, Turkiye.
Seyma TopalDepartment of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Samsun University, Samsun Training and Research Hospital, Samsun, Turkiye.ORCID 0000-0003-2603-4746
Ayse Seza İnalDepartment of Infectious Diseases and Clinical Microbiology, Cukurova University Medical Faculty Hospital, Adana, Turkiye.ORCID 0000-0002-1182-7164
Ayse Özlem MeteDepartment of Infectious Diseases and Clinical Microbiology, Gaziantep University Medical Faculty Hospital, Gaziantep, Turkiye.ORCID 0000-0003-0994-4465
Yasemin Cakır KıymazDepartment of Infectious Diseases and Clinical Microbiology, Sivas Cumhuriyet University Faculty of Medicine, Sivas, Turkiye.ORCID 0000-0001-5510-3216
Fatma EserDepartment of Infectious Diseases and Clinical Microbiology, Ankara Bilkent City Hospital, Ankara, Turkiye.ORCID 0000-0002-0282-6346
Ceren CesurDepartment of Infectious Diseases and Clinical Microbiology, Ankara Bilkent City Hospital, Ankara, Turkiye.
Ayhan AkbulutDepartment of Infectious Diseases and Clinical Microbiology, Fırat University Faculty of Medicine Research Hospital, Elazığ, Turkiye.ORCID 0000-0003-2560-3265
Muhammed BekcibasıDepartment of Infectious Diseases and Clinical Microbiology, Diyarbakir Gazi Yasargil Training and Research Hospital, Diyarbakır, Turkiye.ORCID 0000-0003-0230-9127
İlknur Esen YıldızDepartment of Infectious Diseases and Clinical Microbiology, Recep Tayyip Erdoğan University, Faculty of Medicine Training and Research Hospital, Rize, Turkiye.ORCID 0000-0003-2987-0483
Mehmet Ali AsanDepartment of Infectious Diseases and Clinical Microbiology, Fırat University Faculty of Medicine Research Hospital, Elazığ, Turkiye.ORCID 0000-0002-3681-7923
Pınar CakmakDepartment of Infectious Diseases and Clinical Microbiology, Mardin Training and Research Hospital, Mardin, Turkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionHIV-HBV coinfection is common among individuals living with HIV; therefore, hepatitis B vaccination is recommended. However, vaccine response rates in people living with HIV are lower than those observed in the healthy population. The aim of this study was to determine HBV vaccination rates and identify risk factors affecting vaccine response in people living with HIV. MATERIALS AND

methodsThis multicenter, observational, retrospective study included patients over 18 years of age who were diagnosed with HIV infection and followed for at least six months between January 2018 and January 2024. Patients were screened for HBV using HBsAg, Anti- HBc IgG, and Anti-HBs serology, and Anti-HBs levels were measured at least 4-8 weeks after completion of the HBV vaccination schedule.

resultsOf 811 people living with HIV, 274 met the inclusion criteria. The median age was 37.5 years (range: 18-75), and 85% were male. The hepatitis B vaccination rate in this cohort was 33.7%. Following the HBV vaccination schedule, vaccine response (Anti-HBs ≥10 IU/L) was observed in 73.4% of individuals. Hypertension and chronic obstructive pulmonary disease (COPD) were identified as independent risk factors affecting vaccine response (p = 0.016 and p = 0.026, respectively).

conclusionVaccine response was found to be lower in individuals with hypertension and COPD. These factors should be considered when administering the hepatitis B vaccine to people living with HIV to improve immunization outcomes.

Indexed as

Hepatitis BHepatitis B VaccinesHIV InfectionsVaccinationAdolescentAdultAgedCoinfectionFemaleHepatitis B AntibodiesHumansMaleMiddle AgedRetrospective StudiesRisk FactorsTurkeyHepatitis B AntibodiesHepatitis B VaccinesCOPDhepatitis B vaccinehypertensionPeople living with HIVvaccinationvaccine response

Identifiers

PMID41863124

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.