Evidence map›Paper›PMID 41862887›Full record

SynthesisBMC oral health2026

Impact of an open healing approach on peri-implant mucosa following immediate implant placement with transmucosal provisionalization: a systematic review and meta-analysis.

Charles C Zadikian, Melodie M Clerc, Jean-Louis Zadikian, Stéphane Kerner, Lucas Duong, Juliane Isaac, Benjamin P J Fournier

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in BMC oral health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Charles C ZadikianFaculty of Dental Surgery, Université Paris Cité, Paris, France.ORCID 0000-0001-5513-7790
Melodie M ClercFaculty of Dental Surgery, Université Paris Cité, Paris, France.ORCID 0000-0001-9675-4904
Jean-Louis ZadikianFrench Association of Implantology for General Dental Practitioners, AFOPI, Sarcelles, France.ORCID 0009-0001-8275-4599
Stéphane KernerFaculty of Dental Surgery, Université Paris Cité, Paris, France.ORCID 0000-0003-4326-6741
Lucas DuongFaculty of Dental Surgery, Université Paris Cité, Paris, France.ORCID 0000-0002-1929-9052
Juliane Isaac *Faculty of Dental Surgery, Université Paris Cité, Paris, France.ORCID 0000-0001-7898-022X
Benjamin P J Fournier *Faculty of Dental Surgery, Université Paris Cité, Paris, France. benjamin.fournier@u-paris.fr.ORCID 0000-0003-4383-7524

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare the peri-implant mucosal stability between an “open healing” approach (test) during immediate dental implant placement with bone grafting and immediate transmucosal provisionalization (non-occlusal) versus primary flap closure (control).

methodsThis systematic review followed the PRISMA guidelines. A literature search was conducted in multiple databases up to May 2025. The primary outcome was peri-implant mucosal stability (Midfacial Mucosal Level (MML). Secondary outcomes include peri-implant soft tissue parameters (e.g. Papilla evaluation, mucosal thickness) and bone related outcomes (e.g. Marginal Bone Loss (MBL), buccal bone thickness and implant survival rate).

resultsOut of 362 records, 12 studies were included, representing 431 patients and 438 implants. Most studies demonstrated a low risk of bias, although heterogeneity in outcomes assessment was observed. Meta-analysis showed limited midfacial mucosal changes between control and test groups, showing good stability of peri-implant keratinized tissue. Other soft and hard tissue outcomes were comparable between groups.

conclusionThe open healing approach with bone particle grafting during immediate dental implant placement appears as a viable option for supporting midfacial mucosa and maintaining mucosa and bone stability. However, more high-quality randomized controlled trials are necessary to confirm these findings. CLINICAL RELEVANCE: This minimally invasive protocol appears to provide satisfactory outcomes by preserving peri-implant tissues, thereby reducing the need for multiple surgical interventions.

Indexed as

Dental Implantation, EndosseousDental ImplantsImmediate Dental Implant LoadingMouth MucosaWound HealingBone TransplantationHumansSurgical FlapsDental ImplantsBone graftingImmediate dental implant placementImmediate provisionalizationMeta-analysisOpen-healingPeri-implant mucosaSystematic review

Identifiers

PMID41862887
PMCPMC13126965

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.