Evidence map›Paper›PMID 41862860›Full record

ArticleBMC psychiatry2026

Risk of neuropsychological impairment among therapeutic community residents: relationship with dropout and spontaneous recovery during treatment.

Simon Deniel, Marion Delarue, Louise Quételard, Maïlys Miquel, Stéphane Lozé, Marie Dumont, Christophe Rimbaud, Susie Longbottom, Nicolas Kenens, Nicolas Bourguignon and 5 more

Abstract read
In one paragraph

Article in BMC psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Simon DenielUniversité de Caen Normandie, LPCN UR 7452, Caen, F-14000, France.
Marion DelarueUniversité de Caen Normandie, LPCN UR 7452, Caen, F-14000, France.
Louise QuételardCommunauté Thérapeutique de la Sauvegarde du Nord, Le Cateau- Cambrésis, France.
Maïlys MiquelCommunauté Thérapeutique du the Fleuve, CEID Addictions, Barsac, France.
Stéphane LozéCommunauté Thérapeutique de la Sauvegarde du Nord, Le Cateau- Cambrésis, France.
Marie DumontCommunauté Thérapeutique de la Sauvegarde du Nord, Le Cateau- Cambrésis, France.
Christophe RimbaudCommunauté Thérapeutique du the Fleuve, CEID Addictions, Barsac, France.
Susie LongbottomCommunauté Thérapeutique d'Aubervilliers, Aurore Association, Aubervilliers, France.
Nicolas KenensCommunauté Thérapeutique d'Aubervilliers, Aurore Association, Aubervilliers, France.
Nicolas BourguignonFederation Addiction, Paris, France.
Jonathan RayneauFederation Addiction, Paris, France.
Juliette DupuisFederation Addiction, Paris, France.
Marine GaubertFederation Addiction, Paris, France.
Hélène BeaunieuxUniversité de Caen Normandie, LPCN UR 7452, Caen, F-14000, France.
Ludivine RitzUniversité de Caen Normandie, LPCN UR 7452, Caen, F-14000, France. ludivine.ritz@unicaen.fr.ORCID 0000-0003-0320-8328

Funding

Institut pour la Recherche en Santé Publique IRESP-19-ADDICTIONS-16
6 · The paper itself

Abstract

backgroundTherapeutic Communities (TCs) are long-term residential treatment settings for individuals with substance use disorders, who often present with neuropsychological impairments. These impairments may influence treatment retention, yet little is known about their evolution in TCs or their association with dropout. This study aims to: (1) identify early risk factors for dropout; (2) investigate the potential recovery from the risk of neuropsychological impairment during an 8-mont stay in a TC; and 3) identify variables at TC entry that may predict the risk of neuropsychological impairment during follow-up.

methodsFifty-seven residents from 3 French TCs completed clinical, substance use, and medical assessments, along with a neuropsychological screening (BEARNI) at entry. Twenty-four completed the 8-month follow-up.

resultsThe dropout rate was 47%. The only significant predictor of dropout was the BEARNI total score, with residents at lower risk of neuropsychological impairment more likely to leave the TC prematurely. Among completers, BEARNI total scores improved at follow-up, primarily explained by improvements in balance rather than in cognitive areas. Lower education, unemployment, recent alcohol use, depressive symptoms, and a history of hepatic disease were consistently associated with a higher risk of neuropsychological impairment at both time points.

conclusionsUnlike other treatment settings, the TC care framework may be particularly appropriate and supportive for residents who are more cognitively vulnerable, as they may be better able to benefit from TCs. Motor recovery among those who remain in treatment is encouraging. However, demographic, addiction-related, and comorbidity factors are consistently associated with the risk of neuropsychological impairment, both at baseline and after 8 months, suggesting a stable and persistent influence over time. CLINICAL TRIAL NUMBER: Not applicable.

Indexed as

Patient DropoutsSubstance-Related DisordersTherapeutic CommunityAdultFemaleFollow-Up StudiesFranceHumansMaleMiddle AgedNeuropsychological TestsRisk FactorsAtaxiaCognitive recoveryCognitive screeningDropoutPolysubstance useRisk of neuropsychological impairmentSubstance use disordersTherapeutic communities

Identifiers

PMID41862860
PMCPMC13126905

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.