Evidence map›Paper›PMID 41862730›Full record

Observational studyEye (London, England)2026

Prognostic value of foveal choroidal vascular hyperpermeability on indocyanine green angiography in central serous chorioretinopathy.

Sofiane Khamkhoum, Francine Behar Cohen, Aude Couturier, Alain Gaudric, Elodie Bousquet

Abstract readObservational Study
In one paragraph

Observational study in Eye (London, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sofiane KhamkhoumDepartment of Ophthalmology, Paris Cité University, Lariboisière Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.
Francine Behar CohenDepartment of Ophthalmology, Paris Cité University, OphtalmoPôle, Cochin Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.
Aude CouturierDepartment of Ophthalmology, Paris Cité University, Lariboisière Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.ORCID http://orcid.org/0000-0001-8549-7455
Alain GaudricDepartment of Ophthalmology, Paris Cité University, Lariboisière Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.
Elodie BousquetDepartment of Ophthalmology, Paris Cité University, Lariboisière Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France. elodie.bousquet@aphp.fr.ORCID http://orcid.org/0000-0001-5926-1385

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo assess the association between the foveal location of choroidal vascular hyperpermeability (CVH) on indocyanine green angiography (ICGA) at the first visit and the visual acuity at the end of the follow-up in central serous chorioretinopathy (CSC).

methodsThis retrospective, observational, longitudinal study was conducted in the ophthalmology department of Lariboisière Hospital, Paris, France. Patients with CSC who underwent multimodal imaging, including ICGA, with a follow-up of more than 3 years, were included. The Early Treatment of Diabetic Retinopathy Study (ETDRS) grid was superimposed over mid-phase ICGA images at the first visit to determine CVH location. CVH were classified according to the location of the lesion within the central 3-mm ETDRS circle.

resultsEighty-four eyes of 68 patients with a mean follow-up duration of 6.5 ± 3 years were included. Patients' mean age was 48.3 ± 14.3 years and 59 patients (86.8%) were men. A foveal CVH was identified in 60 eyes (71.4%). The multivariate analysis showed an association between a final visual acuity worse than 0.3 logMAR (20/40 Snellen equivalent) and a lower initial visual acuity (p = 0.001), the presence of gravitational tracts (p = 0.034) and a foveal CVH at the first visit (p = 0.026).

conclusionThis study suggested that the presence of a foveal CVH is associated with a decline in visual acuity over time. Our findings highlighted the importance of performing ICGA at the first visit to assess disease severity and guide the monitoring of CSC patients.

Indexed as

Capillary PermeabilityCentral Serous ChorioretinopathyChoroidFluorescein AngiographyFovea CentralisIndocyanine GreenAdultAgedColoring AgentsFemaleFollow-Up StudiesHumansMaleMiddle AgedPrognosisRetrospective StudiesColoring AgentsIndocyanine Green

Identifiers

PMID41862730
PMCPMC13194702

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.