ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2026
Low-frequency transient-evoked otoacoustic emission characteristics as potential indicators of hearing improvement in acute Ménière's disease: an exploratory analysis.
Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeFluctuating hearing loss in Ménière’s disease (MD) presents a key clinical challenge due to lack of reliable prognostic markers. The clinical value of transient-evoked otoacoustic emissions (TEOAEs) low-frequency components remains underexplored due to technical difficulty in signal extraction. This study profiled the group delay (GD) and magnitude of low-frequency TEOAEs and observed the association with hearing improvement after acute MD episode.
methods31 patients with unilateral MD were prospectively enrolled during the acute phase of cochleovestibular symptoms. TEOAE and pure-tone audiometry were recorded from initial clinic visit through follow-up. Spectral analysis of TEOAEs was conducted at 500, 1000, and 2000 Hz. The affected ears were categorized into “improved” or “nonimproved” group based on a pragmatic ≥ 10 dB gain in pure-tone average (PTA). The contralateral ears served as convenience controls.
resultsNine (29%) of thirty-one affected ears met the criteria for hearing improvement. Our exploratory analyses showed that 500 Hz GD of the improved group was significantly longer (p < 0.026) initially but did not change longitudinally despite PTA improvement.
conclusionTEOAE phase-gradient metrics (GD) at 500 Hz differ between MD patients with and without hearing improvement in our preliminary findings. Profiling low-frequency otoacoustic emission components may possibly reflect the baseline status or reversibility of OHC function related to hearing improvement after an acute episode.
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