ReviewNpj viruses2026
Venezuelan equine encephalitis virus: novel live-attenuated vaccines for inducing complete protective immunity.
Review in Npj viruses, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Alphavirus replicase and regulatory RNA elements in host interactions and viral vector engineering.Journal of virology · 2026Review
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Venezuelan equine encephalitis virus (VEEV) is a mosquito-borne alphavirus that causes severe neuroinflammation and fatal infections in some people. Numerous outbreaks of VEEV have been reported in Latin America in the past century. Though mosquito-borne, studies have demonstrated that aerosolized VEEV infections lead to significantly higher mortality rates in animal models, suggesting that VEEV, if aerosolized, could cause widespread infections. There are currently no FDA-approved vaccines against VEEV, though TC-83, a live-attenuated strain of VEEV, has been tested as an investigational new drug in laboratory personnel and at-risk health workers. Its use, however, has been associated with severe adverse events and variable immunogenicity. Novel live-attenuated vaccines such as the V4020, V3526, VRC-WEVVLP03-00VP, 68U201/IRES1, and others are under development to overcome some of the limitations associated with the TC-83 vaccine. Here, we discuss the pathogenesis of VEEV and the current state of VEEV vaccines that are in clinical development.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.