Evidence map›Paper›PMID 41862487›Full record

ArticleNPJ microgravity2026

Dielectric double shell characterization of yeast cells exposed to simulated microgravity.

Sai Deepika Reddy Yaram, Alexa Bostic, Soumya K Srivastava

Abstract read
In one paragraph

Article in NPJ microgravity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Machine Learning-Based Detection ofPathogens (Basel, Switzerland) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sai Deepika Reddy YaramDepartment of Chemical and Biomedical Engineering, West Virginia University, Morgantown, WV, USA.
Alexa BosticDepartment of Chemical and Biomedical Engineering, West Virginia University, Morgantown, WV, USA.
Soumya K SrivastavaDepartment of Chemical and Biomedical Engineering, West Virginia University, Morgantown, WV, USA. soumya.srivastava@mail.wvu.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microgravity alters key biological processes, impacting cellular structure, function, and metabolism. In the absence of gravity, cells experience changes that disrupt signal transduction, gene expression, and metabolic pathways, affecting growth rates and cellular viability. Ground-based simulators like clinostats replicate microgravity conditions to study these effects, allowing researchers to examine cellular responses in the lab. This study uses Saccharomyces cerevisiae to explore microgravity's impact on yeast metabolism and properties. Yeast cells are exposed to simulated microgravity via a 2D-clinostat and analyzed using dielectrophoresis over 1-24 h. A double-shell model reveals significant morphological and membrane changes under these conditions. Results indicate notable differences in membrane permittivity and conductivity, with microgravity reducing the folding factor in yeast cells, impairing nutrient uptake and energy production. This research enhances the understanding of microgravity's effects on eukaryotic cells and contributes to the field of gravitational biology.

Identifiers

PMID41862487
PMCPMC13168354

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.