Evidence map›Paper›PMID 41862466›Full record

ArticleNature communications2026

Confined-hydrogel fluidic memristor crossbar array for neuromorphic computing.

Guangguo Guo, Tianyi Xiong, Boyang Xie, Jianping Zhang, Jin Zhang, Yinghai Lu, Yueru Zhao, Wenjie Ma, Cong Pan, Yanan Jiang and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Guangguo GuoBeijing National Laboratory for Molecular Science, Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing, China.
Tianyi XiongBeijing National Laboratory for Molecular Science, Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing, China.
Boyang XieBeijing National Laboratory for Molecular Science, Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing, China.
Jianping ZhangBeijing National Laboratory for Molecular Science, Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing, China.
Jin ZhangBeijing National Laboratory for Molecular Science, Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing, China.
Yinghai LuBeijing National Laboratory for Molecular Science, Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing, China.
Yueru ZhaoBeijing National Laboratory for Molecular Science, Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing, China.
Wenjie MaBeijing National Laboratory for Molecular Science, Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing, China.ORCID http://orcid.org/0000-0003-1268-4959
Cong PanBeijing National Laboratory for Molecular Science, Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing, China.
Yanan JiangCollege of Chemistry, Beijing Normal University, Beijing, China.
Lanqun MaoCollege of Chemistry, Beijing Normal University, Beijing, China. lqmao@bnu.edu.cn.ORCID http://orcid.org/0000-0001-8286-9321
Jianhua WangDepartment of Chemistry, College of Sciences, Northeastern University, Shenyang, China. jianhuajrz@mail.neu.edu.cn.
Ping YuBeijing National Laboratory for Molecular Science, Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing, China. yuping@iccas.ac.cn.ORCID http://orcid.org/0000-0002-6096-1933

Funding

National Natural Science Foundation of China (National Science Foundation of China) 22125406, 22550002, T2596021Natural Science Foundation of Beijing Municipality (Beijing Natural Science Foundation) F251009, Z230022, 2242028
6 · The paper itself

Abstract

Replicating brain-like computation with fluidic memristors offers advantages in energy efficiency and chemical responsiveness over solid-state devices, yet scaling remains challenging due to complex fabrication and their amorphous nature. Herein, we developed a confined hydrogel fluidic memristor by forming a gel-gel interface at the micropore orifice. This design with confined hydrogel enables scalable fabrication of a 10×10 fluidic memristor array (FMA) on polyimide micropores. FMA exhibits fundamental neuromorphic behaviors like paired-pulse facilitation/depression, spike-rate-dependent plasticity, and chemical-regulated plasticity. We also used reservoir computing algorithms with FMA to recognize both computer-generated black-and-white digit images and handwritten digits, achieving a classification accuracy of 89.5% on the Modified National Institute of Standards and Technology dataset. This study demonstrates a hydrogel confined fluidic memristor array, paving an avenue for creating large-scale fluidic memristor arrays and hardware intelligence with ions.

Identifiers

PMID41862466
PMCPMC13168566

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.