Evidence map›Paper›PMID 41862107›Full record

ArticleNeuroImage2026

Implant-friendly MRI of deep brain stimulation patients at 3T.

Nur Izzati Huda Zulkarnain, Alireza Sadeghi-Tarakameh, Jeromy Thotland, Noam Harel, Yigitcan Eryaman

Abstract read
In one paragraph

Article in NeuroImage, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nur Izzati Huda ZulkarnainCenter for Magnetic Resonance Research (CMRR), University of Minnesota, 2021 6th Street Southeast, Minneapolis, MN, 55455, USA.
Alireza Sadeghi-TarakamehCenter for Magnetic Resonance Research (CMRR), University of Minnesota, 2021 6th Street Southeast, Minneapolis, MN, 55455, USA.
Jeromy ThotlandCenter for Magnetic Resonance Research (CMRR), University of Minnesota, 2021 6th Street Southeast, Minneapolis, MN, 55455, USA.
Noam HarelCenter for Magnetic Resonance Research (CMRR), University of Minnesota, 2021 6th Street Southeast, Minneapolis, MN, 55455, USA.
Yigitcan EryamanCenter for Magnetic Resonance Research (CMRR), University of Minnesota, 2021 6th Street Southeast, Minneapolis, MN, 55455, USA. Electronic address: yigitcan@umn.edu.

Funding

TRD4 - Ultrahigh Field Engineering and SafetyP41EB027061 · NIBIB · UNIVERSITY OF MINNESOTA · PI Mehmet Akcakaya · 2019 to 2026
$11.7M
Safe Magnetic Resonance Imaging of Patients with Deep Brain Stimulation SystemsR01NS115180 · NINDS · UNIVERSITY OF MINNESOTA · PI ERYAMAN, YIGITCAN · 2020 to 2024
$1.9M
NIBIB NIH HHS P41 EB027061NINDS NIH HHS R01 NS115180
6 · The paper itself

Abstract

introductionMRI of patients with deep brain stimulation (DBS) implants presents a significant safety risk due to RF heating. A current measurement that utilizes an inherent imaging artifact was previously used to mitigate induced current along a single electrode using a two transmit-channel system. This study extends it to bilateral DBS configurations and demonstrates a streamlined implant-friendly (IF) optimization in both unilateral and bilateral patients.

methodsThe bilateral IF mode was optimized to reduce RF-induced currents on both electrodes while maximizing the overall B1 and was validated in an anthropomorphic head phantom. An imaging workflow to determine electrode-specific and bilateral IF modes were demonstrated in three DBS patients (one bilateral, two unilateral). Image quality and artifact reduction of the circularly-polarized (CP) and IF modes were compared using 2D-TSE.

resultsPhantom study confirmed the heating reduction capabilities of the IF optimization. In both phantom and patient studies, RF artifact reduction was observed. In the unilateral DBS case, IF optimization completely mitigated the induced current, while in the bilateral case, current was reduced up to 74 % compared to CP excitation. The total active scan time for the pre-scan imaging was <6 min. All measurements in the pre-scan protocol were performed directly on the MRI console, with minimal external hardware.

conclusionThis study demonstrates a practical workflow for real-time current analysis and IF mode optimization in patients with DBS implants, effectively reducing RF-induced heating and artifacts while maintaining imaging performance.

Indexed as

BrainDeep Brain StimulationElectrodes, ImplantedMagnetic Resonance ImagingArtifactsHumansPhantoms, ImagingRadio WavesDBS implant-friendly optimizationDeep brain stimulation safetyMRIRadiofrequency heating

Identifiers

PMID41862107
PMCPMC13154932

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.