ArticleAddictive behaviors2026
Stimulant use predicts high-risk substance use behaviors during medication treatment for opioid use disorder.
Article in Addictive behaviors, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Brixadi for Stimulant Use Disorder: Evolving Pharmacologic Considerations and Clinical Implications.Advances in therapy · 2026Review
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
backgroundThe fourth wave of the overdose epidemic has been characterized by co-utilization of opioids and stimulants. This combined use is associated with high-risk behaviors, including heroin and intravenous drug use. Because research in real-world settings is limited, the objective of this study was to examine the impact of stimulant use before and during treatment for opioid use disorder on high-risk behaviors (intravenous opioid or stimulant use, heroin use).
methodThe current study included patients who initiated either methadone or buprenorphine from a statewide network of providers in Texas from May 20, 2020 to August 31, 2024. They were all uninsured/underinsured and living below the federal poverty line. We utilized two logistic regressions to examine whether stimulant use before or during treatment predicted heroin use or intravenous stimulant or opioid use.
resultsIn total, 2848 patients were included in this study (M
conclusionsSeparately analyzing stimulant use at treatment initiation and during treatment indicated a time-specific association between stimulant use and high-risk behaviors. Addressing stimulant use concurrent with opioid use will help reduce high-risk behaviors and may improve the prognosis of those using opioids and stimulants.
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Registered trials
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