Evidence map›Paper›PMID 41861205›Full record

ArticleMedicine2026

Combined drug therapy with ultrasound-guided stellate ganglion block for primary tinnitus.

Zhifu Chen, Juan Zhang, Tao Bai, Peirong Yang, Guochang Song, Anjun Yan, Ruiling Wang

Abstract read
In one paragraph

Article in Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zhifu ChenDepartment of Anesthesiology, Bao Ji People's Hospital, Baoji City, Shaanxi Province, China.
Juan ZhangDepartment of Ultrasonic Medicine, Baoji Third People's Hospital, Baoji City, Shaanxi Province, China.
Tao BaiDepartment of Anesthesiology, Bao Ji People's Hospital, Baoji City, Shaanxi Province, China.
Peirong YangDepartment of Endemic Disease Control, Baoji City Center for Disease Control and Prevention, Baoji City, Shaanxi Province, China.
Guochang SongDepartment of Otolaryngology, Bao Ji People's Hospital, Baoji City, Shaanxi Province, China.
Anjun YanDepartment of Anesthesiology, Bao Ji People's Hospital, Baoji City, Shaanxi Province, China.
Ruiling WangDepartment of Anesthesiology, Bao Ji People's Hospital, Baoji City, Shaanxi Province, China.ORCID 0009-0001-7514-053

Funding

Clinical Research and Application of Ultrasound-Guided Stellate Ganglion Block for Neurogenic Tinnitus Treatment 2021SF-265
6 · The paper itself

Abstract

This study aimed to evaluate the effectiveness and safety of combined medication therapy and ultrasound-guided stellate ganglion block treatment for primary tinnitus. This retrospective cohort study reviewed the clinical data of 113 patients with primary tinnitus, with 46 patients receiving stellate ganglion block treatment as the control group and 67 patients receiving the combined medication therapy combined with ultrasound-guided stellate ganglion block treatment as the observation group. Baseline characteristics, tinnitus severity scores, quality of life, psychological health, adverse events, and patient satisfaction were assessed and compared between the 2 treatment groups. Baseline demographics and tinnitus characteristics were similar between groups (P > .05). Posttreatment, the observation group showed significantly greater improvements in tinnitus severity (all metrics, P < .05), quality of life (physical, emotional, role, cognitive, social domains, P < .005), and psychological health (anxiety, depression, stress, sleep, social support, P < .05). Adverse events (headache, dizziness, nausea) were comparable (P > .05). Patient satisfaction favored the observation group (P = .034), though fewer reported "very satisfied". The combined intervention demonstrates superior efficacy across clinical and psychosocial outcomes with comparable safety. Medication therapy combined with ultrasound-guided stellate ganglion block treatment significantly reduces tinnitus severity. However, due to the retrospective observational nature of this study, the findings demonstrate an association rather than a causal relationship.

Indexed as

Autonomic Nerve BlockStellate GanglionTinnitusUltrasonography, InterventionalAdultAgedCombined Modality TherapyFemaleHumansMaleMiddle AgedPatient SatisfactionQuality of LifeRetrospective StudiesTreatment Outcomedrug therapyprimary tinnitusquality of lifeseverityultrasound-guided stellate ganglion block

Identifiers

PMID41861205
PMCPMC13008153

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.