Evidence map›Paper›PMID 41861144›Full record

ArticleEuropean journal of public health2026

Understanding the role of psychological factors in long COVID: a network analysis approach.

Sofia-Marie Oehlke, Andreas Goreis, Annika Lozar, Diana Klinger, Paul L Plener, Michael Zeiler, Oswald D Kothgassner

Abstract read
In one paragraph

Article in European journal of public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sofia-Marie OehlkeDepartment of Child and Adolescent Psychiatry, Medical University of Vienna, Vienna, Austria.ORCID 0000-0002-0633-5827
Andreas GoreisDepartment of Child and Adolescent Psychiatry, Medical University of Vienna, Vienna, Austria.ORCID 0000-0001-8994-964X
Annika LozarDepartment of Child and Adolescent Psychiatry, Medical University of Vienna, Vienna, Austria.ORCID 0009-0008-7694-9323
Diana KlingerDepartment of Child and Adolescent Psychiatry, Medical University of Vienna, Vienna, Austria.ORCID 0000-0002-1959-1088
Paul L PlenerDepartment of Child and Adolescent Psychiatry, Medical University of Vienna, Vienna, Austria.ORCID 0000-0003-4333-1494
Michael ZeilerDepartment of Child and Adolescent Psychiatry, Medical University of Vienna, Vienna, Austria.ORCID 0000-0002-7087-6134
Oswald D KothgassnerDepartment of Child and Adolescent Psychiatry, Medical University of Vienna, Vienna, Austria.ORCID 0000-0002-3243-0238

Funding

European Economic and Social Committee (EWSA)-Fund
6 · The paper itself

Abstract

Long COVID (LC) is a heterogeneous, multisystem condition that persists beyond the acute phase of SARS-CoV-2 infection. Psychological symptoms are highly prevalent and may influence the course and severity of LC. However, their specific role within the broader symptom structure remains insufficiently understood. This study applied a psychological network approach to examine how psychological factors contribute to the overall symptom structure of LC and to identify central and bridging variables that may serve as promising targets for intervention. A sample of 283 individuals with LC (nfemale = 235, nmale = 47, ndiverse = 1; age: M = 39.48, SD = 13.29) completed an online survey assessing post-viral physical symptoms and psychological factors, including depression, anxiety, COVID-19-related traumatic stress, and lack of self-efficacy. A regularized partial correlation network was estimated based on ten variables. The network revealed a dense degree of connectivity, with psychological factors integrated into the broader symptom structure. Depression emerged as the most central variable. Cardiovascular and respiratory symptoms, neurological symptoms, and depression served as key bridge variables. Lack of self-efficacy showed moderate associations with COVID-19-related traumatic stress and anxiety. Female gender was linked to greater gastrointestinal symptom burden, while older age was associated with more pronounced cardiovascular and respiratory symptoms. This study underscores the central role of psychological factors-particularly depression-as key targets for intervention in LC. By advancing the understanding of factors shaping health outcomes in LC, our findings support the integration of psychological approaches into the clinical management of affected individuals.

Indexed as

COVID-19DepressionAdultAnxietyFemaleHumansMaleMiddle AgedPost-Acute COVID-19 SyndromeSARS-CoV-2Self EfficacySurveys and Questionnaires

Identifiers

PMID41861144
PMCPMC13017838

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.