Evidence map›Paper›PMID 41861017›Full record

ArticleScience advances2026

Transcription activation mechanism of a noncanonical DNA damage response pathway by the WYL-activator, DriD.

Rajiv R Singh, Amani Chinni, Emily Cannistraci, Raul Salinas, Sunny Yadav, Kevin Gozzi, Maria A Schumacher

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Rajiv R SinghDepartment of Biochemistry, Duke University Medical Center, 307 Research Dr., Box 3711, Durham, NC 27710, USA.ORCID 0000-0002-1819-2165
Amani ChinniRowland Institute at Harvard, Harvard University, 52 Oxford St., Cambridge, MA 02138, USA.ORCID 0009-0002-4946-1476
Emily CannistraciDepartment of Biochemistry, Duke University Medical Center, 307 Research Dr., Box 3711, Durham, NC 27710, USA.ORCID 0000-0003-1880-9185
Raul SalinasDepartment of Biochemistry, Duke University Medical Center, 307 Research Dr., Box 3711, Durham, NC 27710, USA.ORCID 0000-0001-9011-683X
Sunny YadavDepartment of Biochemistry, Duke University Medical Center, 307 Research Dr., Box 3711, Durham, NC 27710, USA.ORCID 0009-0009-4678-7594
Kevin GozziRowland Institute at Harvard, Harvard University, 52 Oxford St., Cambridge, MA 02138, USA.ORCID 0000-0002-1168-1425
Maria A SchumacherDepartment of Biochemistry, Duke University Medical Center, 307 Research Dr., Box 3711, Durham, NC 27710, USA.ORCID 0000-0002-5264-1120

Funding

Deciphering fundamental biological processes involving protein-nucleic acid interactions at the molecular levelR35GM130290 · NIGMS · DUKE UNIVERSITY · PI Maria Schumacher · 2019 to 2026
$4.9M
NIGMS NIH HHS R35 GM130290
6 · The paper itself

Abstract

DNA damage repair mechanisms are vital for cell survival. In the bacterium,

Indexed as

Bacterial ProteinsCaulobacter crescentusDNA DamageTranscriptional ActivationCryoelectron MicroscopyDNA-Directed RNA PolymerasesDNA RepairDNA, Single-StrandedModels, MolecularPromoter Regions, GeneticProtein BindingBacterial ProteinsDNA-Directed RNA PolymerasesDNA, Single-Stranded

Identifiers

PMID41861017
PMCPMC13004042

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.