Evidence map›Paper›PMID 41860993›Full record

ArticleScience immunology2026

The B cell receptor-mTOR signaling axis restricts the accumulation of lung tissue-resident memory B cells after influenza infection.

Kumari Anupam, Komal Patel, Pradhnesh Andhare, Brittany Henry, Christopher H Hanson, Lizzette Pérez-Pérez, Peggy L Kendall, Brian J Laidlaw

Abstract read
In one paragraph

Article in Science immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Neonatal CD19Frontiers in immunology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kumari AnupamDepartment of Medicine, Washington University School of Medicine, St. Louis, MO, USA.ORCID 0000-0001-8134-9463
Komal PatelDepartment of Medicine, Washington University School of Medicine, St. Louis, MO, USA.ORCID 0009-0003-0053-6219
Pradhnesh AndhareDepartment of Medicine, Washington University School of Medicine, St. Louis, MO, USA.ORCID 0000-0003-2207-8821
Brittany HenryDepartment of Medicine, Washington University School of Medicine, St. Louis, MO, USA.ORCID 0009-0005-6457-0146
Christopher H HansonDepartment of Medicine, Washington University School of Medicine, St. Louis, MO, USA.
Lizzette Pérez-PérezDepartment of Medicine, Washington University School of Medicine, St. Louis, MO, USA.ORCID 0000-0001-5881-4363
Peggy L KendallDepartment of Medicine, Washington University School of Medicine, St. Louis, MO, USA.
Brian J LaidlawDepartment of Medicine, Washington University School of Medicine, St. Louis, MO, USA.ORCID 0000-0001-5707-9256

Funding

Enhancing the antiviral memory B cell responseDP2AI169978 · NIAID · WASHINGTON UNIVERSITY · PI LAIDLAW, BRIAN · 2021 to 2024
$2.2M
Lung-resident memory B cell development and function following influenza virus infectionK22AI153015 · NIAID · WASHINGTON UNIVERSITY · PI LAIDLAW, BRIAN · 2020 to 2021
$270k
NIAID NIH HHS DP2 AI169978NIAID NIH HHS K22 AI153015
6 · The paper itself

Abstract

Lung tissue-resident memory B (B

Indexed as

LungMemory B CellsOrthomyxoviridae InfectionsReceptors, Antigen, B-CellTOR Serine-Threonine KinasesAnimalsEarly Growth Response Protein 2MiceMice, Inbred C57BLNFATC Transcription FactorsSignal TransductionEarly Growth Response Protein 2Egr2 protein, mousemTOR protein, mouseNfatc1 protein, mouseNFATC Transcription FactorsReceptors, Antigen, B-CellTOR Serine-Threonine Kinases

Identifiers

PMID41860993
PMCPMC13249078

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.