Evidence map›Paper›PMID 41860958›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2026

Insights into cephalochordate genome and gene evolution from the early-diverging amphioxus

Yifan Ren, Zepu Miao, Che-Yi Lin, Ludong Yang, Huihui Li, Linda Z Holland, Sung-Jin Cho, Jr-Kai Yu, Jia-Xing Yue

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Insights into cephalochordate genome and gene evolution from the early-diverging amphioxusProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yifan Ren *State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Department of Experimental Research, Sun Yat-sen University Cancer Center, Guangzhou 510060, China.ORCID 0000-0002-5141-8947
Zepu Miao *State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Department of Experimental Research, Sun Yat-sen University Cancer Center, Guangzhou 510060, China.ORCID 0000-0002-9734-682X
Che-Yi LinInstitute of Cellular and Organismic Biology, Academia Sinica, Taipei 11529, Taiwan.
Ludong YangState Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Department of Experimental Research, Sun Yat-sen University Cancer Center, Guangzhou 510060, China.ORCID 0009-0007-6684-5689
Huihui LiState Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Department of Experimental Research, Sun Yat-sen University Cancer Center, Guangzhou 510060, China.
Linda Z HollandMarine Biology Research Division, Scripps Institution of Oceanography, University of California San Diego, La Jolla, CA 92093.ORCID 0000-0003-2960-9437
Sung-Jin ChoDepartment of Biological Sciences and Biotechnology, Chungbuk National University, Cheongju 28644, Republic of Korea.ORCID 0000-0001-6126-6310
Jr-Kai YuInstitute of Cellular and Organismic Biology, Academia Sinica, Taipei 11529, Taiwan.ORCID 0000-0001-8591-0529
Jia-Xing YueState Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Department of Experimental Research, Sun Yat-sen University Cancer Center, Guangzhou 510060, China.ORCID 0000-0002-2122-9221

Funding

Academia Sinica (AS) AS-GC-111-L01| Guangdong Provincial Pearl River Talents Program () 2019QN01Y183Korea Institute of Marine Science and Technology promotion (KIMST) RS-2022-KS221555MOST | National Natural Science Foundation of China (NSFC) 32470663National Research Foundation of Korea (NRF) 2020R1A6A1A06046235National Science and Technology Council of Taiwan 110-2621-B-001-001-MY3National Science and Technology Council of Taiwan 113-2621-B-001-004-MY3NSF (NSF) IOS 1952567Young Talents Program of Sun Yat-sen University Cancer Center YTP-SYSUCC-0042
6 · The paper itself

Abstract

Cephalochordates (amphioxus or lancelet) are considered as living proxies for ancestral chordates due to their key phylogenetic position and slow evolutionary rate. The genomes of living amphioxus thus can help to reveal the genetic basis shaping the evolutionary transition from nonvertebrate animals to vertebrates. To gain a comprehensive understanding of the genome architecture in amphioxus, we generated a chromosome-anchored genome assembly for

Indexed as

Evolution, MolecularGenomeLanceletsAnimalsDNA Transposable ElementsPhylogenySyntenyDNA Transposable Elementsamphioxuscephalochordategenome evolutionHoxsynteny

Identifiers

PMID41860958
PMCPMC13012124

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.