Evidence map›Paper›PMID 41860218›Full record

ArticleApplied and environmental microbiology2026

Characterization of acetovanillone degradation in wild-type and engineered

Anne T Lalande, Megan E Wolf, Logan D Robeck, Lindsay D Eltis

Abstract read
In one paragraph

Article in Applied and environmental microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Anne T LalandeDepartment of Microbiology and Immunology, Life Sciences Institute, The University of British Columbia, Vancouver, BC, Canada.ORCID 0009-0005-8804-9566
Megan E WolfDepartment of Microbiology and Immunology, Life Sciences Institute, The University of British Columbia, Vancouver, BC, Canada.
Logan D RobeckDepartment of Microbiology and Immunology, Life Sciences Institute, The University of British Columbia, Vancouver, BC, Canada.
Lindsay D EltisDepartment of Microbiology and Immunology, Life Sciences Institute, The University of British Columbia, Vancouver, BC, Canada.ORCID 0000-0002-6774-8158

Funding

Natural Sciences and Engineering Research Council of CanadaNatural Sciences and Engineering Research Council of Canada 171359
6 · The paper itself

Abstract

There is considerable interest in harnessing bacterial catabolic activities to valorize lignin-derived compounds. One such class of compounds, hydroxyphenylethanones (HPEs), includes acetovanillone (AV), 4-hydroxyacetophenone (HAP), and acetosyringone (AS). Despite occurring in various industrial streams of lignin, there are few reports on their microbiological degradation. Here, we report that IMPORTANCE: As an abundant polymer in plants, lignin represents a renewable alternative to petroleum as a feedstock in the manufacture of chemicals. Strategies to convert lignin into higher-value compounds couple chemical and biological catalysis, where engineered microorganisms transform chemocatalytically generated mixtures of lignin-derived aromatic compounds, or LDACs. The development of microbial biocatalysts depends on the characterization and engineering of pathways that degrade LDACs. In this study, we identified a pathway that partially degrades an important class of LDACs in

Indexed as

AcetophenonesRhodococcusBacterial ProteinsNaphthols1,4-dihydroxy-2-naphthoic acid4-hydroxyacetophenoneAcetophenonesBacterial ProteinsNaphtholsacetovanillonebiocatalysisco-metabolismlignin

Identifiers

PMID41860218
PMCPMC13101465

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.