Evidence map›Paper›PMID 41859961›Full record

ArticleChemistry & biodiversity2026

LC-HESI-MS/MS Profiling and Evaluation of Antioxidant, Anti-Inflammatory, Anti-α-Amylase, and Anti-Acetylcholinesterase Activities of Rhus tripartitum L. Leaf Extract: In Vitro and In Silico Studies.

Raoudha Ben Ameur, Imen Rekik, Nourhène Hamdaoui, Siwar Soltani, Nathan Téné, Michel Treilhou, Mongi Saoudi, Noureddine Allouche

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemistry & biodiversity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Raoudha Ben AmeurLaboratory of Organic Chemistry LR17ES08, Natural Substances Team, Faculty of Sciences of Sfax, University of Sfax, Sfax, Tunisia.ORCID https://orcid.org/0000-0001-9395-7909
Imen RekikLaboratory of Organic Chemistry LR17ES08, Natural Substances Team, Faculty of Sciences of Sfax, University of Sfax, Sfax, Tunisia.
Nourhène HamdaouiLaboratory of Biomathematics LR22ES01, Faculty of Sciences of Sfax, University of Sfax, Tunisia.
Siwar SoltaniLaboratory of Organic Chemistry LR17ES08, Natural Substances Team, Faculty of Sciences of Sfax, University of Sfax, Sfax, Tunisia.
Nathan TénéEquipe BTSB-EA 7417, Institut National Universitaire Jean-François Champollion, Université De Toulouse, Albi, France.
Michel TreilhouEquipe BTSB-EA 7417, Institut National Universitaire Jean-François Champollion, Université De Toulouse, Albi, France.
Mongi SaoudiLaboratory of Biomathematics LR22ES01, Faculty of Sciences of Sfax, University of Sfax, Tunisia.
Noureddine AlloucheLaboratory of Organic Chemistry LR17ES08, Natural Substances Team, Faculty of Sciences of Sfax, University of Sfax, Sfax, Tunisia.

Funding

Ministry of Higher Education and Scientific Research LR17/ES08
6 · The paper itself

Abstract

This study aims to assess the biological characteristics of Rhus tripartitum leaves and identify their promising biomolecules. The numerous extracts of R. tripartitum leaves were evaluated, in vitro, for their phytochemical profile and antioxidant, anti-acetylcholinesterase, α-amylase, and anti-inflammatory activities. The methanolic and ethyl acetate extracts showed the highest levels of phenolics, flavonoids, and tannins, and exhibited the strongest antioxidant effects in DPPH, FRAP, and TAC assays. Regarding the ethyl acetate extract, it demonstrated the greatest in vitro enzyme inhibitory activity against acetylcholinesterase (IC

Indexed as

alpha-AmylasesAnti-Inflammatory AgentsAntioxidantsCholinesterase InhibitorsPlant ExtractsAcetylcholinesteraseAnimalsBiphenyl CompoundsChromatography, LiquidMolecular Docking SimulationPicratesPlant LeavesTandem Mass Spectrometry1,1-diphenyl-2-picrylhydrazylAcetylcholinesterasealpha-AmylasesAnti-Inflammatory AgentsAntioxidantsBiphenyl CompoundsCholinesterase InhibitorsPicratesPlant Extractsmolecular dockingpharmacokineticspharmacological activitiesR. tripartitum leaves

Identifiers

PMID41859961
PMCPMC13003528

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.