Evidence map›Paper›PMID 41859828›Full record

ArticleEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin2026

Calcium propionate in tortillas - a likely cause of a large outbreak of acute gastrointestinal illness, Finland, 2023.

Veera Varo, Elina Leinonen, Annukka Markkula, Minna Anthoni, Marja Raatikainen, Maria Tirkkonen, Nina Gynther, Heidi Landgren, Merja Korkalainen, Ruska Rimhanen-Finne

Abstract read
In one paragraph

Article in Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Veera VaroDepartment of Public Health, Institute for Health and Welfare, Helsinki, Finland.
Elina LeinonenMicrobiological Food Safety Unit, Finnish Food Authority, Helsinki, Finland.
Annukka MarkkulaMicrobiological Food Safety Unit, Finnish Food Authority, Helsinki, Finland.
Minna AnthoniChemical Food Safety Unit, Finnish Food Authority, Helsinki, Finland.
Marja RaatikainenChemistry Unit, Finnish Food Authority, Helsinki, Finland.
Maria TirkkonenEnvironmental services of the Mikkeli region, Mikkeli, Finland.
Nina GyntherEnvironmental services of the Mikkeli region, Mikkeli, Finland.
Heidi LandgrenDepartment of Public Health, Institute for Health and Welfare, Helsinki, Finland.
Merja KorkalainenDepartment of Public Health, Institute for Health and Welfare, Helsinki, Finland.
Ruska Rimhanen-FinneDepartment of Public Health, Institute for Health and Welfare, Helsinki, Finland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In August 2023, 721 individuals became ill with gastrointestinal symptoms in 17 schools in a Finnish municipality. Of these, 323 (45%) developed quickly passing symptoms during school lunch or < 30 min after the lunch. In a questionnaire-based retrospective cohort study, consumption of flour tortillas and vegetable filling served at lunch were statistically associated with illness (adjusted odds ratio (aOR) = 3.3; 95% confidence interval (CI): 1.4-7.4 for the tortillas and aOR = 1.5; 95% CI: 1.1-2.1 for the filling). Abnormal odour was observed in five of nine tortilla samples. In three samples from tortillas produced during a limited production period, high concentrations of calcium propionate (E 282) were measured (> 24,000 mg/kg), exceeding the regulatory maximum limit of 2,000 mg/kg. The tortillas served at lunch were traced to a manufacturer in another EU country. The manufacturer was unable to identify any cause in the production process that could explain the high concentrations of calcium propionate. Our results are in line with findings from other investigations that excessive calcium propionate can induce gastrointestinal symptoms. The investigation highlights the need for strengthened surveillance of chemical-related food-borne outbreaks in Europe and timely communication between school staff and public health authorities to support rapid outbreak detection and response.

Indexed as

Disease OutbreaksFood ContaminationGastrointestinal DiseasesPropionatesAdolescentChildFemaleFinlandHumansLunchMaleRetrospective StudiesSchoolsSurveys and QuestionnairesPropionatescalcium propionatechemicaloutbreakschool lunchtortilla

Identifiers

PMID41859828
PMCPMC13235651

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.