Evidence map›Paper›PMID 41859687›Full record

ArticleOxford open immunology2026

ImmUQBench: a benchmark on uncertainty quantification of protein immunogenicity prediction.

Alif Bin Abdul Qayyum, Amir Hossein Rahmati, Xiaoning Qian, Byung-Jun Yoon

Abstract read
In one paragraph

Article in Oxford open immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Alif Bin Abdul QayyumDepartment of Electrical and Computer Engineering, Texas A&M University, College Station, TX 77843, United States.ORCID https://orcid.org/0009-0008-0706-2913
Amir Hossein RahmatiDepartment of Electrical and Computer Engineering, Texas A&M University, College Station, TX 77843, United States.ORCID https://orcid.org/0009-0001-2981-875X
Xiaoning QianDepartment of Electrical and Computer Engineering, Texas A&M University, College Station, TX 77843, United States.ORCID https://orcid.org/0000-0002-4347-2476
Byung-Jun YoonDepartment of Electrical and Computer Engineering, Texas A&M University, College Station, TX 77843, United States.ORCID https://orcid.org/0000-0001-9328-1101

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Discovering antigen proteins, capable of eliciting desired immune responses, is of paramount importance in developing immunogenic therapeutics for combating various diseases, particularly autoimmune disorders, infectious diseases, as well as cancers. Despite recent advances in artificial intelligence (AI) and machine learning (ML), accurate and generalizable immunogenicity prediction remains challenging due to limited labeled data and model over-simplifications. Uncertainty quantification (UQ) approaches are commonly used to address the aforementioned challenges when applying AI/ML methods with limited training data, aiming to reduce the risk of catastrophic errors. This study aims to systematically evaluate the performance of UQ methods for antigen immunogenicity prediction and to establish a benchmark for assessing model reliability in data-scarce setting. We here present

Indexed as

Bayesian Neural Network (BNN)immunogenicity predictionmulti-modal representation learningProtein Language Model (PLM)Uncertainty Quantification (UQ)variational inference

Identifiers

PMID41859687
PMCPMC12996882

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.