Evidence map›Paper›PMID 41859593›Full record

ArticleCureus2026

Diffuse Bilateral Pseudo-Cystic Pulmonary Lesions Revealing Metastatic Lung Adenocarcinoma: A Case Report and Literature Review.

Nabil Tiresse, Abdelhalim Boucaid, Raihana Laamim, Khalil Chafi, Hicham Souhi

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Translational lung cancer research · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nabil TiresseDepartment of Pneumology, Mohamed VI Military Hospital, Dakhla, MAR.
Abdelhalim BoucaidDepartment of Pneumology, Mohamed V Military Training Hospital, Rabat, MAR.
Raihana LaamimDepartment of Pneumology, Mohamed V Military Training Hospital, Rabat, MAR.
Khalil ChafiDepartment of Diagnostic Radiology, Mohamed VI Military Hospital, Dakhla, MAR.
Hicham SouhiDepartment of Pneumology, Mohamed V Military Training Hospital, Rabat, MAR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diffuse cystic lung diseases are a heterogeneous group of disorders with multiple etiologies, including rare malignant causes. We report the case of a 49-year-old non-smoking man presenting with a two-month history of dry cough without hemoptysis, dyspnea, or chest pain. Chest computed tomography (CT) revealed diffuse bilateral pseudo-cystic pulmonary lesions and scattered nodules. Bone window analysis identified osteolytic lesions of the sternum and the eighth thoracic vertebra. Additional CT scans demonstrated multiple secondary lesions involving the brain, spine, and left iliac bone. 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) showed hypermetabolic pulmonary, mediastinal, and skeletal lesions. Brain and spinal magnetic resonance imaging confirmed multiple cerebral and vertebral secondary localizations, with perimedullary tumoral epiduritis. A CT-guided biopsy of the sternal lytic lesion established the diagnosis of poorly differentiated lung adenocarcinoma. Tumor cells expressed thyroid transcription factor-1 and cytokeratin AE1/AE3, with programmed death-ligand 1 expression <1%. Molecular analysis revealed no mutations in EGFR, KRAS, BRAF, HER2, or MET. Systemic chemotherapy with carboplatin and pemetrexed was initiated, with pembrolizumab planned, and radiotherapy was administered for the vertebral lesion. This case highlights a rare pseudo-cystic radiological presentation of metastatic lung adenocarcinoma and underscores the importance of considering a neoplastic etiology in patients presenting with diffuse bilateral thin-walled pulmonary lesions.

Indexed as

ct scan chestdiffuse cystic lung diseasemetastatic adenocarcinoma of lungmolecular targeted therapypet scanspseudo-cystic pulmonary lesions

Identifiers

PMID41859593
PMCPMC12998972

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.