ReviewCureus2026
Prevalence, Clinical Profile, and Outcomes of Diabetic Ketoacidosis (DKA) in Pediatric ICU Patients in the Middle East: A Systematic Review and Meta-Analysis.
Review in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Diabetic ketoacidosis (DKA) is a life-threatening complication of type 1 diabetes mellitus (T1DM) in children. While the global incidence is rising, data on the clinical profile and outcomes of pediatric DKA specifically within intensive care units (ICUs) in the Middle East remain fragmented. This systematic review and meta-analysis aimed to synthesize evidence on the prevalence, severity, and clinical outcomes of DKA in pediatric ICU settings across the region. PubMed, Embase, Scopus, Web of Science, and WHO Global Index Medicus were searched for observational studies published from January 2000 to December 2025. Studies were included if they reported on pediatric patients (0-18 years) with DKA admitted to ICUs in Middle Eastern countries. Two reviewers independently screened the studies, extracted data, and assessed their quality using the Joanna Briggs Institute (JBI) checklist and Newcastle-Ottawa Scale (NOS). A random-effects meta-analysis was conducted to estimate the pooled prevalence and clinical parameters. Six studies comprising 919 pediatric patients from Saudi Arabia, Egypt, and Iran met the inclusion criteria. The pooled prevalence of severe DKA (pH<7.1) among ICU admissions was 37% (95% confidence interval (CI): 28%-46%), with substantial heterogeneity (I
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