Evidence map›Paper›PMID 41859412›Full record

SynthesisFrontiers in neurology

A bibliometric analysis of alpha-synuclein in Parkinson's disease from 2015 to 2024.

Liangman Xiao, Shumin Lin, Yixuan Wu, Xin Liu, Danxia Gu, Jingqi Fan, Lixing Zhuang

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Frontiers in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Liangman XiaoFirst Clinical Medical College, Guangzhou University of CM, Guangzhou, Guangdong Province, China.
Shumin LinFirst Clinical Medical College, Guangzhou University of CM, Guangzhou, Guangdong Province, China.
Yixuan WuFirst Clinical Medical College, Guangzhou University of CM, Guangzhou, Guangdong Province, China.
Xin LiuFirst Affiliated Hospital of Guangzhou University of CM, Guangzhou, Guangdong Province, China.
Danxia GuFirst Clinical Medical College, Guangzhou University of CM, Guangzhou, Guangdong Province, China.
Jingqi FanFirst Affiliated Hospital of Guangzhou University of CM, Guangzhou, Guangdong Province, China.
Lixing ZhuangFirst Affiliated Hospital of Guangzhou University of CM, Guangzhou, Guangdong Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study employs bibliometric analysis to systematically examine global research trends and map the intellectual landscape of α-synuclein (α-syn) in Parkinson's disease (PD) from 2015 to 2024. Methods: On January 14, 2025, bibliographic data were extracted from the web of science core collection (WOSCC) and PubMed. Using CiteSpace (version 6.2.R4), VOSviewer (version 1.6.20), the Bibliometrix R package (4.4.2), and Microsoft Excel 2024, we analyzed publication trends, geographic and institutional contributions, journal distributions, author distributions, co-cited references, and keyword co-occurrences. Results: A total of 10,390 publications were included, with a steady annual growth (R Conclusion: The significance of α-syn in Parkinson's disease research is growing. Future efforts should emphasize mechanistic studies, biomarker validation, and targeted therapies to advance personalized medicine in PD.

Indexed as

alpha-synucleinbibliometricsParkinson’s diseasePubMedweb of science core collection

Identifiers

PMID41859412
PMCPMC12995758

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.