Evidence map›Paper›PMID 41859404›Full record

ArticleFrontiers in neurology

Different types of electrostimulation target specific impaired sensory and motor functions in chemotherapy-induced peripheral neuropathy: a secondary analysis of a controlled trial.

Florian Rieder, Robert Sassmann, Yvonne Theres Kienberger, Vanessa Castagnaviz, Dagmar Schaffler-Schaden, Tim Johansson, Gabriel Rinnerthaler, Maria Flamm, Richard Greil, Christoph Schulze and 1 more

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03978585 (Comparison of High Tone Therapy and TENS Therapy in Chemotherapy-induced Polyneuropathy), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03978585 nacompletednot on this map

Comparison of High Tone Therapy and TENS Therapy in Chemotherapy-induced Polyneuropathy

TypeinterventionalSponsorParacelsus Medical UniversityRan2019 to 2021Enrolled51ConditionsPeripheral Nervous System ProblemArmshigh tone external muscle stimulation, transcutaneous electrical nerve stimulation (TENS) therapy
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Florian RiederInstitute of Physical Medicine and Rehabilitation, Paracelsus Medical University, Salzburg, Austria.
Robert SassmannInstitute of Physical Medicine and Rehabilitation, Paracelsus Medical University, Salzburg, Austria.
Yvonne Theres KienbergerInstitute of Physical Medicine and Rehabilitation, Paracelsus Medical University, Salzburg, Austria.
Vanessa CastagnavizIIIrd Medical Department with Haematology, Medical Oncology, Haemostaseology, Infectiology and Rheumatology, Oncologic Center, Paracelsus Medical University, Salzburg, Austria.
Dagmar Schaffler-SchadenInstitute of General Practice, Family Medicine and Preventive Medicine, Paracelsus Medical University, Salzburg, Austria.
Tim JohanssonSalzburg Regional Health Fund (SAGES), Salzburg, Austria.
Gabriel RinnerthalerDivision of Clinical Oncology, Department of Internal Medicine, Medical University of Graz, Graz, Austria.
Maria FlammInstitute of General Practice, Family Medicine and Preventive Medicine, Paracelsus Medical University, Salzburg, Austria.
Richard GreilIIIrd Medical Department with Haematology, Medical Oncology, Haemostaseology, Infectiology and Rheumatology, Oncologic Center, Paracelsus Medical University, Salzburg, Austria.
Christoph SchulzeInstitute of Physical Medicine and Rehabilitation, Paracelsus Medical University, Salzburg, Austria.
Simon Peter GampenriederIIIrd Medical Department with Haematology, Medical Oncology, Haemostaseology, Infectiology and Rheumatology, Oncologic Center, Paracelsus Medical University, Salzburg, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: We performed a secondary data analysis of a previously published study to investigate the effects of different electrical stimulation modalities on specific impaired sensory and motor functions. Methods: A total of 51 patients with chemotherapy-induced peripheral neuropathy (CIPN) ≥ grade 1 after receiving platinum- and/or taxane-based chemotherapy were randomized to 8 weeks of high-tone external muscle stimulation (HTEMS) or transcutaneous electrical nerve stimulation (TENS). A control group ( Results: For sensory function categories, HTEMS significantly improved tingling in the fingers or hands ( Conclusion: Electrotherapy is a useful tool for treating CIPN. A symptom-oriented selection of the stimulation modality may be promising. Clinical trial registration: https://clinicaltrials.gov/ct2/show/NCT03978585.

Indexed as

CIPNelectrotherapyHTEMSQLQ-CIPN20TENS

Identifiers

PMID41859404
PMCPMC12995806

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.