ArticleFood chemistry. Molecular sciences2026
Identification of a unique tea germplasm exhibiting hyperaccumulation of trans-catechins and its molecular regulatory mechanism.
Article in Food chemistry. Molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Catechins are the principal bioactive components in tea, and their trans-isomers offer superior benefits such as tea quality, and support human health when compared with their predominant cis-forms. This study aims to identify natural tea germplasm that is rich in trans-catechins and hypothesizes that such a unique catechin composition can broadly reshape the metabolism of other flavor compounds. Herein, a unique germplasm, Y5, was identified and comprehensively profiled. Metabolomic and quantitative analysis revealed that Y5 preferentially hyperaccumulates trans-catechins over cis-catechins, with gallocatechin gallate (GCG) reaching 70.1 ± 0.3 mg/g (over 50-fold higher than controls). Moreover, Y5 exhibited rare co-accumulation of theobromine and caffeine, along with increased levels of specific proanthocyanidins and anthocyanin derivatives. The amino acid profiles changed accordingly as well. Molecular investigation revealed a coordinated regulatory network that redirects biosynthetic flux toward the trans-catechins pathway. The redirection of metabolic flux was largely affected by the late biosynthetic genes and transporters rather than the early biosynthetic genes. Serine carboxypeptidase-like acyltransferases (SCPLs) and multidrug and toxic extrusion transporters (MATEs) were identified as the key genes that facilitate GCG hyperaccumulation. This study provides a valuable resource for catechin research and a foundation for the development of GCG-rich natural tea beverages.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.