Evidence map›Paper›PMID 41859345›Full record

ArticleJournal of oral biology and craniofacial research

Long-term ion release, fluoride recharge, pH modulation, and mechanical aging of an experimental ACP-based composite compared with contemporary bioactive restorative materials.

Anshuman Shetty, Mohammed Abdul Saleem, Ameer Akhil Ahmed Shaik, Mohammed Mustafa, Rahul Tiwari, Tanisha Shetty

Abstract read
In one paragraph

Article in Journal of oral biology and craniofacial research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anshuman ShettyDepartment of Conservative Dentistry and Endodontics, NITTE (Deemed to be University) AB Shetty Memorial Institute of Dental Sciences Deralakatte, Mangaluru, Karnataka, 575018, India.
Mohammed Abdul SaleemDepartment of Oral and Maxillofacial Surgery, Naseem Jeddah Medical Center, Al Oudabaa, Aziziyah, Jeddah, 23342, Saudi Arabia.
Ameer Akhil Ahmed ShaikNarayana Dental College & Hospital, Nellore, Andhra Pradesh, 524003, India.
Mohammed MustafaDepartment of Conservative Dental Sciences, College of Dentistry, Prince Sattam Bin Abdulaziz University, Al-Kharj, 11942, Saudi Arabia.
Rahul TiwariDepartment of Dental Research Cell, Dr. D. Y. Patil Dental College and Hospital, Dr. D. Y. Patil Vidyapeeth (Deemed to be University). Pimpri, Pune, 411018, India.
Tanisha ShettyDepartment of Conservative Dentistry and Endodontics, NITTE (Deemed to be University) AB Shetty Memorial Institute of Dental Sciences Deralakatte, Mangaluru, Karnataka, 575018, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: This study evaluated the 12-month ion release, fluoride recharge capacity, pH modulation, mechanical aging, and structural reliability of an experimental amorphous calcium phosphate (ACP)-based composite compared to contemporary bioactive restorative materials. Methods: An experimental ACP composite was compared with Activa™ BioACTIVE-Restorative, Cention N, and Surefil one ™. Calcium (Ca Results: All materials exhibited an initial burst of ion release, followed by a progressive decline (p = 0.001). The ACP composite demonstrated the highest early calcium and phosphate release but negligible fluoride release and significant reductions in mechanical properties and reliability after aging. Cention N showed sustained multi-ion release, the greatest alkalizing capacity, and stable mechanical performance. Surefil one™ achieved the highest fluoride release and recharge capacity while maintaining a near-neutral pH and superior mechanical reliability. The Activa™ BioACTIVE-Restorative exhibited moderate ion release and intermediate mechanical performance. Conclusions: Bioactive restorative materials exhibit distinct material-dependent behaviors. Alkasite-based systems showed balanced ion release and mechanical stability, fluoride-focused systems demonstrated superior recharge and reliability, and the ACP composite provided primarily short-term calcium-phosphate release with limited long-term durability.

Indexed as

BioactivityCalcium phosphate nanoparticlesDental compositesFluoride rechargeMechanical properties

Identifiers

PMID41859345
PMCPMC12997216

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.