Evidence map›Paper›PMID 41859339›Full record

ArticleFrontiers in pharmacology2026

Investigations of the voltage-gated Ca

Najeeb Ur Rehman, Mohd Nazam Ansari, Nasser Abdulaziz Alalaiwah, Eyad Omar Alotibi, Aman Karim, Tiegist Bahta, Khalil Y Abujheisha, Muhammad Noman

Abstract read
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Article in Frontiers in pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Najeeb Ur RehmanDepartment of Pharmacology and Toxicology, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia.
Mohd Nazam AnsariDepartment of Pharmacology and Toxicology, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia.
Nasser Abdulaziz AlalaiwahDepartment of Pharmacology and Toxicology, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia.
Eyad Omar AlotibiDepartment of Pharmacology and Toxicology, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia.
Aman KarimDepartment of Biological Sciences, National University of Medical Sciences Rawalpindi, Rawalpindi, Pakistan.
Tiegist BahtaDepartment of Pharmacy, College of Health Sciences, Aksum University, Aksum, Ethiopia.
Khalil Y AbujheishaDepartment of Basic Medical Science, Faculty of Medicine and Health Science, Palestine Polytechnic University, Hebron, Palestine.
Muhammad NomanDepartment of Pharmacy Quaid-i-Azam University Islamabad, Islamabad, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The leaves of Methods: Castor-oil-induced diarrhea was used to assess the diarrheal protection of the extract in mice, while CaCl Results: The extract protected mice from castor-oil-mediated diarrhea significantly compared to the saline control group at doses of 200 and 400 mg/kg. In the isolated jejunum, the extract inhibited both spontaneous and high K Conclusion: The present study is a pilot report on the detailed pharmacodynamics of the antispasmodic effects of the crude extract of

Indexed as

antispasmodicCa++ channel blockerOtostegia fruticosaphosphodiesterase inhibitorverapamil

Identifiers

PMID41859339
PMCPMC12995762

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.