Evidence map›Paper›PMID 41859329›Full record

ArticleCureus2026

Acute Reversible Convergent Strabismus Following Accidental Lorazepam Ingestion in a Child: A Rare Ocular Manifestation of Benzodiazepine Toxicity.

Omayma El Athmani, Leila Debono, Youssef Jeddi, Nour Mekaoui, Lamya Karboubi

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Omayma El AthmaniPediatrics, Children's Hospital, University Hospital Center Ibn Sina, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, MAR.
Leila DebonoPediatric Emergency Medicine, Children's Hospital, University Hospital Center Ibn Sina, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, MAR.
Youssef JeddiPediatric Emergency Medicine, Children's Hospital, University Hospital Center Ibn Sina, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, MAR.
Nour MekaouiPediatric Emergency Medicine, Children's Hospital, University Hospital Center Ibn Sina, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, MAR.
Lamya KarboubiPediatric Emergency Medicine, Children's Hospital, University Hospital Center Ibn Sina, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, MAR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Benzodiazepine intoxication in children commonly manifests with central nervous system depression, hypotonia, and ataxia. Ocular motor abnormalities are uncommon and may mimic serious neurological disorders, frequently prompting urgent neuroimaging. We report the case of an eight-year-old boy who presented with sudden-onset convergent strabismus approximately 30 minutes after accidental ingestion of 10 mg of lorazepam. On admission, he was hemodynamically stable with a Glasgow Coma Scale score of 15/15. Neurological examination was unremarkable except for acute esotropia. Brain computed tomography revealed no abnormalities, and urine toxicology screening was positive for benzodiazepines. The patient was managed conservatively with close clinical observation without administration of flumazenil. Complete spontaneous resolution of the ocular deviation occurred within 12 hours. This case highlights that isolated acute strabismus may represent a rare but reversible manifestation of benzodiazepine intoxication in children. Awareness of this presentation may help clinicians consider toxicological causes in the differential diagnosis and avoid unnecessary invasive investigations.

Indexed as

acute strabismusbenzodiazepine intoxicationesotropialorazepam poisoningpediatric poisoningtoxicology

Identifiers

PMID41859329
PMCPMC12995505

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.