Evidence map›Paper›PMID 41859267›Full record

ArticleFrontiers in public health2026

Mental health of caregivers for people with dementia and cerebral palsy as a key determinant of caregiver burden: a multivariable analysis.

Alba Sánchez-Gil, Andrea Calleja-Caballero, Fátima Pérez-Robledo, Carlos Martín-Sánchez, María Rodríguez-Lorenzo, María Martínez-Romo, Enrique Pérez-Saez, Pedro Manuel Rodríguez-Muñoz, Cristina Rivera-Picón, Jesus Perez and 1 more

Abstract read
In one paragraph

Article in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Alba Sánchez-GilNational Centre of Reference for People with Alzheimer's Disease and Other Dementias, Salamanca, Spain.
Andrea Calleja-CaballeroDepartamento de Enfermería y Fisioterapia, Instituto de Investigación Biomédica de Salamanca (IBSAL), Universidad de Salamanca, Salamanca, Spain.
Fátima Pérez-RobledoDepartamento de Enfermería y Fisioterapia, Instituto de Investigación Biomédica de Salamanca (IBSAL), Universidad de Salamanca, Salamanca, Spain.
Carlos Martín-SánchezDepartamento de Enfermería y Fisioterapia, Instituto de Investigación Biomédica de Salamanca (IBSAL), Universidad de Salamanca, Salamanca, Spain.
María Rodríguez-LorenzoMaster's Degree in Intervention for People with Alzheimer's Disease, Faculty of Medicine, University of Salamanca, Salamanca, Spain.
María Martínez-RomoMaster's Degree in Intervention for People with Alzheimer's Disease, Faculty of Medicine, University of Salamanca, Salamanca, Spain.
Enrique Pérez-SaezNational Centre of Reference for People with Alzheimer's Disease and Other Dementias, Salamanca, Spain.
Pedro Manuel Rodríguez-MuñozFacultad de Enfermería y Fisioterapia, Universidad de Castilla-La Mancha, Toledo, Spain.
Cristina Rivera-PicónFacultad de Enfermería y Fisioterapia, Universidad de Castilla-La Mancha, Talavera de la Reina, Spain.
Jesus PerezDepartamento de Medicina, Instituto de Investigación Biomédica de Salamanca (IBSAL), Universidad de Salamanca, Salamanca, Spain.
Juan Luis Sánchez-GonzálezDepartamento de Medicina, Instituto de Investigación Biomédica de Salamanca (IBSAL), Universidad de Salamanca, Salamanca, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Informal caregiving plays a vital role in supporting dependent individuals; however, prolonged caregiving is associated with significant physical and psychological strain. Understanding factors associated with caregiver burden is essential for designing effective interventions to protect caregiver health and sustain long-term care systems. Objective: To examine the associations between psychological, physical, and contextual factors on caregiver burden and to identify variables independently associated with caregiver burden. Methods: A cross-sectional study was conducted with 73 informal caregivers of people living with dementia or cerebral palsy who required substantial assistance in daily living. Standardized instruments were used to assess caregiver burden (Zarit Burden Interview), anxiety and depression (HADS), mental health and quality of life (SF-36), pain (VAS), and physical activity (IPAQ). Hierarchical multiple regression, mediation, and moderation analyses were performed. Results: Mental health and anxiety showed the strongest independent associations of caregiver burden ( Conclusion: Caregiver mental health is a key determinant of perceived burden of caring for people with dementia and cerebral palsy, exerting a stronger influence than patient dependence or physical demands. Interventions should integrate psychological screening and mental health support to prevent caregiver distress and ensure a sustainable informal care.

Indexed as

Caregiver BurdenCaregiversCerebral PalsyCost of IllnessDementiaMental HealthAdultAgedAnxietyCross-Sectional StudiesDepressionFemaleHumansMaleMiddle AgedMultivariate Analysisanxietyburdencaregiverdepressionmental healthmoderation analysis

Identifiers

PMID41859267
PMCPMC12995671

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.