Evidence map›Paper›PMID 41859255›Full record

ReviewFrontiers in public health2026

Epidemiology of invasive meningococcal disease in the United States: review of recent data and identified risk factors.

Jessica Presa, Daniel Spitz, Paul Balmer, Vincenza Snow, Kathleen Dooling

Abstract readReview
In one paragraph

Review in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jessica PresaUS Medical Affairs, Vaccines and Antivirals, Pfizer Inc, Collegeville, PA, United States.
Daniel SpitzUS Medical Affairs, Vaccines and Antivirals, Pfizer Inc, Collegeville, PA, United States.
Paul BalmerUS Medical Affairs, Vaccines and Antivirals, Pfizer Inc, Collegeville, PA, United States.
Vincenza SnowUS Medical Affairs, Vaccines and Antivirals, Pfizer Inc, Collegeville, PA, United States.
Kathleen DoolingUS Medical Affairs, Vaccines and Antivirals, Pfizer Inc, Collegeville, PA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Tracking the spread of invasive meningococcal disease (IMD) in the United States is important for identifying risk factors and devising public health strategies to prevent infection. Methods: The epidemiology of IMD in the United States before, during, and after the COVID-19 pandemic (2016-2024) was assessed using surveillance data from the National Notifiable Diseases Surveillance System (NNDSS) and the Enhanced Meningococcal Disease Surveillance program (EMDS). Results: IMD case numbers declined during the pandemic (2020-2021) to 208 in 2021 but rebounded to 312 in 2022 and have continued to increase through 2024 (provisionally 477 cases). In 2022, serogroup C was the predominant serogroup (107 cases), followed by serogroup B (61 cases). Except during the pandemic, IMD cases were higher among those attending versus not attending college. During and after the pandemic, groups with the highest IMD incidence were those <1 year of age (range, 0.38-0.56 cases per 100,000 persons) and within the Black population (range, 0.09-0.19 cases per 100,000 persons). The percentage of IMD cases occurring after the pandemic in men who have sex with men and those with HIV increased substantially from during the pandemic. The percentage of IMD cases that occurred among people experiencing homelessness (PEH) was relatively high, ranging from 2.4-6.3%. Conclusion: The data indicate a rebound in IMD after the COVID-19 pandemic, highlighting the importance of strengthening surveillance and vaccination among high-risk populations.

Indexed as

COVID-19Meningococcal InfectionsAdolescentAdultChildChild, PreschoolFemaleHumansIncidenceInfantMaleMiddle AgedPopulation SurveillanceRisk FactorsUnited StatesYoung Adultepidemiologyhigh-risk groupinvasive meningococcal diseasesurveillancevaccines

Identifiers

PMID41859255
PMCPMC12996253

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.