Evidence map›Paper›PMID 41859187›Full record

ArticleToxicology reports2026

Optimization of an

Mikala Melchiors, Mette Stub, Louise Ramhøj, Eleni Barmpari, Kieu-Mi Tran, Anna Opstrup Bindel, Anna Kjerstine Rosenmai, Terje Svingen

Abstract read
In one paragraph

Article in Toxicology reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mikala MelchiorsNational Food Institute, Technical University of Denmark, Kgs. Lyngby, DK-2800, Denmark.
Mette StubNational Food Institute, Technical University of Denmark, Kgs. Lyngby, DK-2800, Denmark.
Louise RamhøjNational Food Institute, Technical University of Denmark, Kgs. Lyngby, DK-2800, Denmark.
Eleni BarmpariNational Food Institute, Technical University of Denmark, Kgs. Lyngby, DK-2800, Denmark.
Kieu-Mi TranNational Food Institute, Technical University of Denmark, Kgs. Lyngby, DK-2800, Denmark.
Anna Opstrup BindelNational Food Institute, Technical University of Denmark, Kgs. Lyngby, DK-2800, Denmark.
Anna Kjerstine RosenmaiNational Food Institute, Technical University of Denmark, Kgs. Lyngby, DK-2800, Denmark.
Terje SvingenNational Food Institute, Technical University of Denmark, Kgs. Lyngby, DK-2800, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thyroid hormone (TH) synthesis and secretion can be perturbed by endocrine disrupting chemicals (EDCs). Traditional 2D cell culture models are useful for studying specific effects on enzymes and transporters involved in hormone synthesis; however, they lack the structural organization required for hormone production. In this study, we refine the conditions for an

Indexed as

ExplantEx vivoThyroid disruptionThyroid glandThyroperoxidase

Identifiers

PMID41859187
PMCPMC12997294

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.