SynthesisFrontiers in medicine2026
Mapping the intellectual landscape and emerging trends of retinitis pigmentosa research.
Synthesis in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: To visualize the intellectual landscape of retinitis pigmentosa (RP) research, outline recent advances, identify emerging trends, and offer insights into future directions. Methods: A bibliometric analysis was conducted on RP-related publications retrieved from the Web of Science and PubMed databases (retrieved on 12 December 2024) using CiteSpace and VOSviewer. The analysis focused on visualizing key dimensions, including annual publication volume, highly cited publications, and keyword distribution. Results: Analysis of 8,121 publications identified four main evolutionary stages: early epidemiological characterization, foundational genetic research, a transition toward clinical trials, and recent therapeutic innovation. Initial studies focused on disease mechanisms, whereas current research is largely oriented toward treatment. The field has become increasingly interdisciplinary, with close links among genetics, bioengineering, nanomedicine, and artificial intelligence-based diagnostics contributing to progress. Keyword burst analysis showed sustained research interest through 2024 in topics such as "optical coherence tomography angiography", "retinal organoid", and "cell death". In addition, "gene therapy" and "oxidative stress" emerged as highly active and rapidly developing research themes. Conclusion: RP research is progressing quickly, with a clear emphasis on therapeutic strategies. The integration of multiple scientific disciplines has accelerated the development of new treatment approaches. Among these, gene therapy and antioxidant-based interventions show strong potential, particularly when used in combination, and represent promising directions for future breakthroughs in RP management.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.