ArticleFrontiers in medicine2026
Efficacy and safety of through-the-scope twin clip for endoscopic closure of gastrointestinal defects.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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11 authors.
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Abstract
Background and aims: The widespread adoption of endoscopic therapy has made the closure of gastrointestinal defects a critical limiting factor for its advancement. Recently, a novel device-the through-the-scope twin clip (TTS-TC)-has been introduced for endoscopic defect closure. This study aimed to evaluate the safety and efficacy of TTS-TC. Methods: A retrospective observational study was conducted at a territory center, involving patients who underwent endoscopic closure using the TTS-TC from February 2023 to December 2023. The TTS-TC features an additional fixed support column centrally positioned between the bilateral metal clips, enabling independent operation. We collected data on patient demographics, lesion characteristics, endoscopic closure time, procedural outcomes, and post-procedural outcomes, including adverse events. Results: Among the 36 recruited patients (22 male, 14 female), the mean age was 61 ± 12 years. Most interventions were performed in the stomach (61.1%). Indications for clip application included hemostasis of acute ulcer bleeding ( Conclusion: The TTS-TC emerges as a promising tool for the closure of diverse gastrointestinal defects, offering a new dimension in endoscopic management.
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