ArticleInfection and drug resistance2026
Impact of Dexamethasone on Respiratory Sequelae in the Follow-Up of Hospitalized Patients with Sars-Cov-2 Pneumonia.
Article in Infection and drug resistance, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Clinical and Radiological Outcomes of Organising Pneumonia Secondary to COVID-19: A 2-Year Longitudinal Cohort Study.Journal of clinical medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Dexamethasone has been shown to reduce 28-day mortality in COVID-19 patients requiring oxygen, but its effect on long-term pulmonary complications remains unclear. This study aimed to assess whether treatment with dexamethasone in the acute phase of SARS-CoV-2 pneumonia improves post-COVID clinical outcomes. Methods: This longitudinal retrospective study analysed patients hospitalized for SARS-CoV-2 pneumonia between March 2020 and April 2021. Patients were stratified according to dexamethasone treatment during hospitalization. They were evaluated 3-9 months post- discharge using clinical assessments, pulmonary function tests, and imaging studies. We compared the demographic, clinical, and functional characteristics according to dexamethasone treatment. Multivariate linear and logistic regression models were used to assess the association between dexamethasone and main outcome follow-up variables. Results: In a study of 1,011 patients hospitalized for SARS-CoV-2 pneumonia, 663 received dexamethasone treatment while 348 did not. During post-COVID follow-up, dexamethasone-treated patients reported less dyspnea (28.4% vs 37.6%, p=0.003); showed better lung function, particularly in DLCO (76.9% vs 69.9%, p<0.001), and better performance in the 6-minute walk test (435 meters vs 405 meters, p=0.002) Radiologically, these patients had lower degrees of reticulation (4,4% vs 9,5%; p=0,009), septal thickening (5,8% vs 10,5%; p=0,012) and fibrosis (3,5% vs 15,6%; p=<0,001). Although rates of bronchial involvement were similar, dexamethasone-treated patients had less bronchiolitis but more bronchiectasis and bronchial thickening. Dexamethasone treatment increased DLCO by 9.25 points (95% CI: 0.50-18.00; p=0.038) and significantly reduced the risk of fibrosis (OR=0.24; 95% CI: 0.12-0.49) in multivariate analysis. Conclusion: Patients treated with dexamethasone showed improved post-COVID respiratory outcomes, including less dyspnea, better lung function, and fewer signs of fibrosis. These findings suggest that dexamethasone is associated with improved outcomes after severe COVID-19 pneumonia.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.