Trial reportJournal of pain research2026
Postoperative Pain After Transapical Beating-Heart Septal Myectomy for Hypertrophic Obstructive Cardiomyopathy: A Retrospective Study.
Trial report in Journal of pain research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
8 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Objective: This study aimed to evaluate the postoperative pain in patients with hypertrophic cardiomyopathy who underwent transapical beating-heart septal myectomy (TA-BSM) and to explore whether a thoracic paravertebral nerve block (TPVB) can effectively alleviate the postoperative pain resulting from this surgical procedure. Methods: Patients aged 18-75 years, classified as American Society of Anesthesiologists II-III, who underwent TA-BSM between April and September 2023, were included. A total of 197 patients were initially enrolled and evaluated in this study. Following the application of the inclusion and exclusion criteria, 136 participants were allocated to two cohorts: a control group (CON group) and a TPVB group, based on whether a TPVB was administered before the surgical intervention. Demographic data, perioperative characteristics, visual analog scale scores, analgesic strategy, and Quality of recovery-15 scores were evaluated. Results: After inverse probability of treatment weighting (IPTW) adjustment, the standardized mean difference in baseline characteristics between the two groups was <0.1. The incidence of moderate-to-severe pain on postoperative day 7 was 51.7% in the TPVB group compared to 71.1% in the CON group. The adjusted relative risk for moderate-to-severe pain was 0.748 [95% CI, 0.565 to 0.990] via IPTW analysis. The oral morphine equivalent administered via PCA during the initial 48 hours post-surgery was significantly lower in the TPVB group than in the CON group (225 vs 195; median difference, 34.5 [95% CI, 21 to 48]; Conclusion: Preoperative administration of a single TPVB before TA-BSM was associated with a reduced postoperative pain intensity, ranging from moderate to severe, and a subsequent decrease in opioid usage. TPVB may be a beneficial analgesic strategy for patients undergoing TA-BSM.
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