Evidence map›Paper›PMID 41858479›Full record

ArticleJournal of surgical case reports2026

A case of metaplastic breast cancer presenting as a fungating breast wound.

Brendan M Flynn, Amy M Wang, Nicholas L Michael, Ariel N Kleydman, Matthew D Nealeigh

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of surgical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Brendan M FlynnDepartment of Surgery, The Walter Reed National Military Medical Center, 8901 Rockville Pike, Bethesda, MD 20814, United States.
Amy M WangDepartment of Surgery, The Walter Reed National Military Medical Center, 8901 Rockville Pike, Bethesda, MD 20814, United States.
Nicholas L MichaelDepartment of Surgery, The Walter Reed National Military Medical Center, 8901 Rockville Pike, Bethesda, MD 20814, United States.
Ariel N KleydmanDepartment of Pathology, The Walter Reed National Military Medical Center, 8901 Rockville Pike, Bethesda, MD 20814, United States.
Matthew D NealeighDepartment of Surgery, The Walter Reed National Military Medical Center, 8901 Rockville Pike, Bethesda, MD 20814, United States.ORCID https://orcid.org/0000-0002-1264-3375

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metaplastic breast cancer (MBC) is a rare and aggressive breast neoplasm, accounting for less than 1% of all breast cancer diagnoses. We report the case of a 74-year-old female who presented with a rapidly enlarging breast mass causing a worsening, non-healing wound. A biopsy was consistent with metaplastic breast cancer, and the patient underwent upfront surgery and adjuvant chemotherapy. Unfortunately, after three rounds of chemotherapy, she passed away at home without a clear etiology. Histopathologic diagnosis can be challenging due to the variety of cell types and associated metaplasia involved. This case demonstrates a dramatic presentation of metaplastic breast cancer and the challenges associated with diagnosing and treating this rare disease.

Indexed as

aggressive breast malignancyfungating breast massmastectomymetaplastic breast cancer

Identifiers

PMID41858479
PMCPMC12998213

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.